We tried 40 peptides in 1 year – our reviews and top picks!

Before embracing short-chain peptides, we were leaving so many healing opportunities out of our toolbox.

This post is my apology to the peptide universe for not sooner unleashing their potential.

As a mea culpa, they are front and center and we admit – essential on any journey to better health!

More of our story is below, but first, a look at what we’re going to review.

Hopefully something for everyone!


Note from me Dec. 2025 – I’m so grateful for the kind comments from readers who found this post useful 🤍

In the year following this 40 peptide exploration, I’ve written much more content! Some of it is now linked within this post.

And you can find it all on our comprehensive Peptide Resources Page

So if there’s anything you don’t find here, it might be there.

I believe this post is still the best starting point for information – Thank you for being here!


Contents

Links skip to corresponding section.

They are all oral peptides except where noted.

Best Peptides for:
  • Brain: CogniPep (subcortical brain & blood vessels) – increase memory, focus, attention, recall and wellbeing #5
  • Mast Cells, inflammation, antifungal, antimicrobial, PANS, allergies: KPV #1
  • Thyroid: ThyroPep – improve energy, stabilize body systems, reduce brain fog & more #6
  • Longevity, anti-aging & sleep: PinealPep / Epithalon / Endoluten (pineal gland – endocrine system) #8, 13 & 25 (also DSIP spray or Selank spray for sleep #11 & 15)
  • Stress response: Hypotalen, Endocron + Adrenact (hypothalumus, pituitary & adrenal) – HPA axis repair #32 & 33
  • Anxiety: Selank / Adalank (nasal spray) #15
  • Metabolism, energy, weight management & longevity: 5-Amino-1 MQ #10 (small molecule)
  • Skin elasticity & joints: Collacell – Collagen Bioregulator #41
  • Repair of damaged tissues: TB4 Frag – for any injuries or toxin exposure #2 (reminder, red / IR light therapy with the contact method can also help with healing – see our post)
    • New: Nerve pain: ARA 290 – reduces inflammation, pain, promotes regeneration
  • Immunity: Thymogen Alpha 1 – thymic peptide (^Th1) #3 and VIP (^Th2) #18
  • Gut Lining: Larazotide Acetate – close tight junctions – reduces intestinal permeability #9 Also for repair, Gastrogen (New!)
  • Peri / menopause: See our Hormones Over 40 post. For success, we need to focus on these areas: Ovaries, Adrenals (take over much of the hormone production), Pituitary (supports hormones), Pineal (longevity & circadian rhythm), Thyroid (temperature regulation & energy), metabolism, skin elasticity & joints
  • Pairing with other peptides: Ventfort (blood vessels) – improve delivery & reach #21
  • Organ of your choice: see applicable bioregulator below
  • Mitochondria: NAD+ (link to our post about this small molecule which is better than the mito peptides)

All mentioned peptides

Peptides / Combination Bioregulators: KPV, TB4 Frag, Thymogen A1, CerebroPep, CogniPep, ThyroPep, KPV Spray, PinealPep, Can’t Weight, BPC-157, Larazotide, 5-Amino-1 MQ

Peptide Nasal Sprays: DSIP, Epithalon, P21, Oxytocin, Selank / Adalank, Semax / Adamax, VIP

Single Organ Bioregulator (short-chain) Peptides: General Bioregulator info, Lungs, Blood Vessels, Brain (CNS), Stomach, Liver, Pancreas, Kidney, Bone Marrow, Pituitary, Pineal, Adrenals, Ovaries, Eyes, Bladder, Thyroid, Heart, Muscles, Cartilage, Skin & Joints

🧬 New: Our Complete Bioregulator Peptide Guide!

Helpful Information: Peptides 101For sensitive peoplePulsing & breaksSignaling DurationBioregulator FAQAcetylation & AmidationSpray reconstitution Tips for organizing peptidesPeptide StorageOur current stacksDiscounts & Coupon codes

New: Dosing Info only Page – brief overview for each peptide we routinely mention


Consolidated Links to Purchase

You can click on the product name next to its number in this blog post but some have asked for a consolidated list – here it is:

• Or see this Shopping List Style pdf


Our Experience

After 16 years of helping my daughter reach her optimal health, I needed to admit – mine was not thriving!

I had POTS, long COVID, mast cell activation, internal tremors, brain fog, lightheadedness, post exertional malaise (needed to rest from sweeping the floor), temperature dysregulation, and was developing new allergies by the month.

I felt at least 10 years older than my age.

I also had to admit – I wasn’t giving it my all.

I wasn’t researching or trialing treatments like I would if it was for my daughter.

When I finally decided to take myself on as a patient, I started to solve the puzzle!

Peptides have given us a new lease on life! 

The long list of issues began to resolve – including my nearly lifelong allergies, asthma, IBS and POTS.

Recent bloodwork biomarkers gave me a biological age of 10 years less – which matches how I feel – and is a 20 year swing!

Also on this journey, peptides helped my daughter and friends with a wide variety of health needs.


NEW: For help personalizing any of this:

You can text or call my digital mind!

Peptides 101

Peptides are small chains of amino acids held together by peptide bonds.
They are the building blocks of proteins.

Peptides are messengers to our cells.

These influencers – long before social mediabind to receptors on our cells instructing them how to carry out bodily processes.

Each peptide’s message is determined by its specific sequence of amino acids.

Image: Dr. Kent Holthorf 

They can regulate hormone release, cell growth, tissue repair, skin regeneration, blood sugar control, microbial attacks, immune response, and much more.

Bioregulator Peptides are even smaller chains and I’ll explain their unique features in the bioregulator section

For more on Peptides 101, see our page:

Are 40 peptides needed?

A video we once watched, created by someone who bought ALL the American Girl dolls 😳 comes to mind, but nonetheless here we are!

The short answer is, no – but you probably need more than one or two.

Peptide studies consistently show they work even better used in combination – to support an entire body system.

We tried so many because almost all of them helped and we are committed to the cause!


In addition to the newfound health I mentioned at the beginning, my brain feels like it did in my 30’s, sharper and no brain fog.

I no longer struggle to find words or remember why I walked to a room.

Even the texture & elasticity of my skin have undergone very noticeable changes from oral bioregulator peptides – with no new topicsl skincare products! 

I like that a sleep tracker thinks my scores are excellent, but more importantly – I feel rested, energized and ready for each day.


My daughter escaped a recent virus without a post viral PANS flare for the first time in her life.

She’s speaking more clearly, has greater cognition and word retrieval, less anxiety, is calmer and happier! 

Physically, she has improved in both small and gross motor skills!

Her mast cells have quieted and she no longer gets red heat rashes or bug bite welts.

Peptides have given us larger health gains than anything else – and if you’ve followed us for a while, you know that includes a lot!

So, if that required trying 40 peptides, I would sign up all over again!

From earlier days of our blog 🤍

Special Considerations for Sensitive people

Before we get to the list, I’d like to highlight some tips to make peptide use most successful if you’re sensitive, like us!

  • Always begin with smaller doses.
    • Peptides can be very potent and even a small amount can work well.
    • We like to start with very tiny doses, as small as 1/6 cap (1/10th for KPV) and adjust upward.
  • You can use the powder sublingually – some bioregulators are available as liquid drops.
  • Time of Day – brain peptides should only be taken in the morning. We typically try to take most peptides earlier in the day, unless they are for sleep.
  • Die off – The only peptide in this list that may result in die off symptoms is KPV. Read more in the KPV blog post.
  • Peptides are safe to use alongside almost any supplement or medicine and they can be combined with one another – always verify if concerned
  • It’s ok to go slow!

Continual use vs. Pulsing vs. Longer Breaks

Peptides and bioregulators get to work immediately – many of them bringing changes shortly after taking the first dose.

To see effects involving healing of tissues or organs will take longer of course!

You can take them as long as needed and take breaks as needed too.

•••

Some people use pulse dosing others do not. 

1. Examples of pulsing options:

  • 4 weeks on – then 10 days per month on / 20 days off 
  • 4 weeks on – several months off 
  • 5 days on / 2 days off
  • 3 days on / 1 day off

2. No Pulse option: 

  • Smaller amounts (a portion of the capsule) with no scheduled breaks
  • Breaks be taken anytime and restart if needed 
  • Can be better for sensitive people

We use the second method (small amounts continuous until we want a break) for all of them —

— except the brain peptides / bioregulators which can become too stimulating even at low doses if you never pause.

Opening capsules and taking fractions of them is not difficult and doses don’t need to be exact

For more peptide dosing tips, information about signaling duration and more, see our video:


Signaling Duration

Most peptides do not last long in the body. It’s always better to use more frequent dosing when getting started.

After a few weeks, you can use them less frequently.

*exception for those that are time of day specific such as those for Thyroid, Adrenals or Cognition – only to be taken in the morning


Housekeeping info

As always, our site is ad-free and has no sponsors. Writing about health topics has been a hobby of mine since 2009.

I’m arranging this massive list by brand and approximately chronologically based on our usage.

I’m not anticipating it will be read in one sitting!

• Use the Contents section to skip to parts that interest you and come back as often as you like, the post isn’t going anywhere ☺️

• All dosing amounts are very approximate and I encourage everyone to decide for themselves what works best


Coupon Codes

Here are coupons for each of the brands we use. They are unlimited in use. Click on Brand for their website

Integrative Peptides: SAVE10 

Biolab: RESTORE

VitaStream: BIOREG10

Limitless Life: QUALITY (20% off, stackable if they have a sale)

• Coupon codes are also under product photos at the start of each section and listed at the end.

• Clicking on a peptide name (next to its number) will take you to the product page on the brand website •


Integrative Peptides

Discount Coupon at Integrative Peptides:
SAVE10 for 10% off (unlimited use)
free shipping

I definitely recommend this one. While inner changes are fundamental to our health, it’s also a nice treat to see some additional aesthetic changes!

1. KPV – Mast cells, inflammation, yeast, bacteria

The first peptide we tried was a home run!

I read about it as an option to calm mast cells if nothing else worked.

While I would argue it should be tried first, I’m thankful it opened my eyes to the world of peptides!

It not only calmed mast cells (rashes, food intolerance, asthma and allergies), it decreased inflammation, yeast, bloating, cured every skin condition including my daughter’s acne, reversed SIBO and has been a staple in our home.

It’s even been effective in helping my daughter avoid a PANS flare.

Our dose: has changed over time – ranging from a micro dose (every few hours), up to 1.5 capsules – divided through the day (too much) and back down to a maintenance daily micro dose.

BUY HERE: integrativepeptides.com/product/kpv/

10% off with coupon: SAVE10

Many more essential details and dosing discussion are in our KPV blog post.

Please read it if you’re going to take this one!

How the KPV peptide calmed our mast cells, GI tract, and inflammation

•••

A comment from a group member

(The second peptide we tried, Larazotide Acetate (LA) pairs well with KPV. It closes tight junctions in the gut and you will find it at #9 below)


2. TB4 Frag – Healing damaged tissues

We began using TB4 Frag to promote gut healing.

We’ve now seen it noticeably speed many real-world healing examples ~

  • Post‑workout muscle recovery and a sprained back resolved faster with better range.
  • My plantar fasciitis is a thing of the past.
  • Gut healing has also happened quickly and for kids – cuts, scrapes, and bug bites all resolve faster with less scarring. It has even helped soothe sore throats.
  • We’ve also seen everyday bruises clear faster, a signal of it’s active tissue remodeling.
  • We are definite fans of this healing peptide & consider it a medicine cabinet essential!

Healing from toxin exposure is also significantly quicker and more complete with TB4 Frag onboard.

I’ve heard it’s so effective at clearing damaged tissue it can prevent a hangover if taken before drinking! 🍷🍺 (Damage from acetaldehyde building up in the blood causes a hangover)

Similarly, it can repair damage from other toxins you’ve been exposed to, even in the past.

Imagine the healing possibilities!

Studies have shown it’s effective enough to reverse damage from a heart attack.

It supports both Stem cell activation and migration

It can create new blood vessels in areas that need more blood flow – excellent to pair with a cognition peptide.

Thymosin B(4) frag is a very small amino acid chain that plays an important role in protection, regeneration, and remodeling of injured or damaged tissues.

“Tβ4 has substantial potential for.. MS/EAE or other neurological demyelinating diseases, with the remyelination effect supplementing its anti-inflammatory and neuroprotective role.” (R)

Our Dose: Less than 1/4 capsule 1-3x per day

BUY HERE: integrativepeptides.com/product/tb4-frag 10% off with coupon: SAVE10

I’m always careful with immune acting peptides, but we tolerate it well, it seems to be a true modulator (not a booster).

Also available: – (At above link only now)

TB4 Frag Oral Spray – which could also work well sprayed on skin in need of healing (we used KPV Spray topically with great success!)

TB4 Frag Max with added thymus peptide (can be too immune stimulating for some)

For much more about TBF Frag see our post:

TB4‑Frag’s Edge on Tissue Healing – for all ages & stages! (Comparison to BPC 157 and TB 500)


3. Thymogen Alpha 1 – Thymus gland / immune system

Our thymus controls T cells, critical for fighting viruses, infections and foreign substances by recognizing and attacking them.

Recently, when we both had a cold virus, I gave this peptide a try.

The first time in my daughters life that she did not have a post viral PANS flare!

We were using both KPV and a small amount of Thymogen.

Balance in the Immune System

Thymic peptides, while modulating, are generally known to promote a shift toward a stronger Th1 immune response.

This shift is important if you need to fight a virus or have Th2 dominance.

However, sometimes people lean toward a Th1 dominant immune response and I suspect we do.

We have always felt worse when taking thymic proteins and peptides (in the absence of an acute viral condition).

For other people like us, the VIP a peptide shifts toward Th2 and our review of it is later in this post.

We can successfully take Thymogen when we need immune activation to fight a virus

Our Dose (when sick): 1/4 cap – 3x a day (approximate, can use more)

We stopped taking TA 1 when we were about 3/4 of the way back to healthy.

It did not flare other symptoms and we had no post viral conditions – a huge win!

BUY HERE: integrativepeptides.com/product/thymogen-alpha-1

10% off with coupon: SAVE10

Thymogen is a critical part of our protocol which has gotten us and others recovered in 1 day – when started immediately 🤍


4. CerebroPep – Subcortical Brain / Central Nervous System

This brain peptide – aka oral Cerebrolysin – really delivers!

From Integrative Peptides:

“A special formulation of porcine derived peptide blend brings the highest standard in quality and safety to support cognitive health and well-being.

Similar to other porcine neuro peptides such as Cerebrolysin, which is administered through injection, CerebroPep ™ marks the entrance of Integrative Peptides into the neuro and cognitive space without a needle.”

A new blend, Cognipep (below) contains the same brain peptides plus additional blood vessel peptides to enhance reach into the brain.

Please read both sections because the CNS specific peptides are the same and I didn’t duplicate info.

If you’re in the Facebook Chat Group, you may have read my post about Cerebropep:

Our Dose: 1/4 cap 1-2x per day – Morning and noon only

As with other brain supplements (eg. nootropics or choline) they could interfere with sleep if taken too late.

I usually cycle this one – Approximately 5 days on, 2 days off.

Sometimes we see more gains on days off. Almost like the brain has a chance to shine after working overtime on repair.

BUY HERE: integrativepeptides.com/product/cerebropep

10% off with coupon: SAVE10

We have replaced it with CogniPep:


5. CogniPep – Subcortical brain + blood vessel peptides

This peptide is responsible for turning back the clock on my brain about 20 years!

The combination of brain and vascular peptides is a winning one.

If you haven’t read the CerebroPep section directly above, I suggest starting there because the brain portion of this peptide is the same and I didn’t duplicate info.

Cerebropep vs. CogniPep

CerebroPep’s benefits seemed very slightly splintered while CogniPep feels all encompassing.

Every function of my brain was noticeably and simultaneously improved.

Most likely:

• The added vascular bioregulator in CogniPep allows the peptides to travel deeper into the brain

• There may have been areas CerebroPep was not quite reaching

My daughter is having incredible cognitive gains as well. She’s speaking with words I have never heard her use and is very focused, centered and her happiest self!

She’s also more physically active, running faster and doing new complex yoga positions!

Our Dose: I’m taking approx 1/4 cap in the morning. My daughter takes even less ~ 1/6 cap.

You can take more initially – we are on a maintenance dose.

We like to take short breaks from this one. Sometimes 5 days on and 1-2 days off.

It is possible to have your brain feel slightly sluggish as it’s repairing and then noticeably better on the days off, everyone reacts differently.

We don’t take it later in the day because it could interfere with sleep.

BUY HERE: integrativepeptides.com/product/cognipep-60-caps

10% off with coupon: SAVE10

A report was recently released that estimated nearly half of Americans face dementia risk.

When I saw the headline, I thought ~ “Not if they use brain peptides!”

Subcortical brain structures CogniPep can help optimize:

  • Basal Ganglia – motor control, movement
  • Hippocampus – memory, learning (including emotions & smells)
  • Thalamus – consciousness, sleep, learning and language processing
  • Amygdala – emotion processing
  • Pituitary – hormone production & stress response
  • White matter – neural networks for rapid transmission of signals between brain regions

I cannot more highly recommend this peptide.

I see no side effects and we’ve been taking it about a month.

Others I’ve talked to are experiencing the same benefits.

It definitely sets the bar high for any other brain peptide!

When we started Pinealon, I was very impressed 🤓

When we switched to CerebroPep, I was even more impressed 🧐

When we switched to CogniPep, I was thoroughly stunned 🤯

6. ThyroPep – Thyroid bioregulator

This is starting to sound like an ad, but ThyroPep is the best thyroid supplement I’ve ever taken!

It gave me increased energy, better sleep, temperature regulation, brought stability to my body (not so sensitive to everything) and turned around the last of my remaining health issues.

Optimizing your thyroid can also decrease brain fog.

Reasons ThyroPep works dramatically better than the Thyroid Bioregulators you will see below:

  • It’s Acetylated and Amidated – more bioavailable, lasts longer, closer matches our own peptides.
  • It contains bioregulator peptides and glandulars – with T4 and T3 removed.
  • It contains additional (3 total) bioregulators.
  • See my post below and this video I made for my comparison of each

It can be taken by people with hypo or hyper thyroid conditions and / or autoimmune thyroid issues such as Hashimoto’s) and bring all of us back to balance!

(We dive into bioregulators more in a below section.)

Here’s what I had to say:

Something else I learned:

We are often told thyroid issues require weight issues for diagnosis, this study says otherwise – Relationship between thyroid dysfunction and body weight: A not so evident paradigm

Other people are having amazing success in our FB group too. For example:

From: Diary of Recovery Peptide Chat on Facebook

My Dose: 1 cap per day when I wake up (empty stomach).

Some people take this peptide for 1 month and then 10 consecutive days out of each following month.

I have not pulsed it yet and have been taking for 3 months

BUY HERE: integrativepeptides.com/product/thyropep

10% off with coupon: SAVE10

It comes in 30 and 60ct bottles so look for the smaller one if you want to give it a test.

Five stars for ThyroPep! ⭐️⭐️⭐️⭐️⭐️


7. KPV Spray – works topically too!

I originally didn’t purchase this spray because I wanted to microdose and it would be more difficult than with capsules.

However, we found a great use for it! It works amazingly well topically for skin irritations – bug bites, scalp issues (most are fungal related).

Recently, during a cold, we had very painful sinuses and it seemed an infection could be looking.

I decided to spray it in my palm and dab it with a fingertip on the skin over our sinuses – upper cheeks & under the eyes.

Not only did no sinus infection occur, but I realized that KPV works transdermally in the same way that small doses of the capsules work!

I’m a big fan of this spray and plan to keep it as a staple in my medicine cabinet.


8. PinealPep – Pineal Gland

Let’s talk about this important small gland and why pineal peptides are considered essential for slowing aging.

A primary function of the pineal is to produce melatonin, therefore regulating circadian rhythm.

Anther critical function is maintaining the length of our telomeres.

Telomeres are the protective caps at the ends of chromosomes.

They shorten with each cell division, leading to cellular senescence (aging) when they become too short. 

This supplement is a blend of 3 bioregulators combined to give superior results compared to pineal gland bioregulators taken alone.

It’s been said that if you’re going to use just one bioregulator, it should be the pineal gland.

People have referred to it as the master regulator & conductor of the endocrine orchestra.

Because PinealPep also contains 20% thymus peptides, we are going slowly.

For now, we take 1/8 cap, alongside other pineal products you will see reviewed below.

If you’re only using this one I’d start with 1/4 cap and go up from there.

Always in the evening, a few hours before bed.

My daughter fell fast asleep, happily, on the first night we used it!

BUY HERE: integrativepeptides.com/product/pinealpep-60-caps

10% off with coupon: SAVE10

Note: careful consideration is encouraged if giving pineal supplements (or melatonin) to kids who haven’t hit puberty.

FAQ: What Can Pineal Bioregulator Peptides Help With?


Peptides we haven’t used but want to mention
BPC 157 – ‘Body Protection Compound’

This peptide was an early darling in the peptide world.

It may seem like a glaring omission that we haven’t tried it.

But it can cause anxiety and / or mast cell activation in sensitive people. Some have reported anhedonia. I have never felt comfortable with that risk profile.

I also can’t recommend anything to others that could cause those issues and and people in our group do report these same side effects.

Others do use it without problems and praise its effectiveness, so everyone needs to decide from themselves!

(Also note BPC is in the Gut Feeling blend along with probiotics, also which we do not use https://recoveringkids.fom/probiotics)


PetTides 🐶

A blend of KPV, BPC-157 and Immune peptides, in oil, for your pet.


Can’t Weight

This peptide has reduced hunger for several people I trust to review it and they are happily losing weight!

• For fat cell metabolism & weight loss, also see: 5-AMINO-1 MQ (below)

Coming soon from Integrative Peptides:

• GIPep • Stem Cell Bioregulators • Mitochondria Bioregulators • for now see: NAD+ for our best pick to support mitochondria

We *can’t wait!*

Note: Shipping out of the USA is often possible if you email cs@integrativepeptides.com


The importance of Acetylation and Amidation

Here’s an article if you’d like to read more about this topic.


Click here to go back up to the Contents List


Biolab

•••
Discount Coupon at Biolab:
RESTORE will give you a discount

Ordering from Biolab (overseas) can sometimes be a trying experience.

Credit cards can be declined, connecting with customer service can be challenging and I feel terrible anytime someone has issues. One person received nearly expired products and while the potency of peptides is long, beware of these issues.

When you can get them, we have found them to be effective, good quality and well priced (even including the costly shipping).

Another positive – Their nasal sprays are prepared with saline rather than water (Limitless) which is much more soothing to use!

We have a Peptide FAQ detailing how people have used PayPal when their credit card was declined.

You can purchase many of the same peptides from Limitless in the USA (indicated below)


9. Larazotide Acetate – gut tight junctions

This narrowly directed peptide is excellent for closing the tight junctions in the gut and throughout the body, including the brain.

It’s very useful to prevent die off – from using KPV or any type of antimicrobial or detox – from escaping the gut and re-entering your body.

My dose: 1/4 capsule 3x a day (before meals) it works within approx 10 minutes

It has no taste so it’s easy to use sublingually, avoiding the brightly colored capsules 😬

It only works while you take it, it’s not designed to heal, just to close tight junctions in the gut.

I stopped taking it for a while but started again – I feel better with it!

BUY HERE: https://biolabshop.eu/preparations-for-regeneration/229-laro.html

Coupon Code: RESTORE

****It’s also available from Limitless Biotech in the USA (see below). Theirs is now Amidated and works even better than Biolab ****

Buy from Limitless (discount for 20% off w/ code: QUALITY – here: https://www.limitlesslifenootropics.com/product/n-acetyl-larazotide-amidate/

If you’re interested, here’s my post for much more info and price comparison: Larazotide acetate – This tight junction regulator closed our “leaky guts”


10. 5-AMINO-1 MQ – Longevity, Fat cell metabolism & energy

The first day I started taking this small molecule (not technically a peptide but often discussed in same circles), I noticed such an increase in energy I thought it had to be a coincidence.

The second day I realized it wasn’t!

Just 1/4 cap had me doing lunges while brushing teeth, hauling in heavy grocery bags at lightening speed, and cleaning my house like I haven’t in, ever!

I wouldn’t say I was sluggish before but it unlocks a whole new level of energy.

A good info page about 5Amino1MQ with studies is here

How does it deliver this full charge?

  • Inhibits the enzyme NNMT – this burns more fat cells by correcting their metabolism.*
  • Increases NAD+ and activates the longevity gene, SIRT1
  • Increases muscle mass by rerouting our energy expenditure to burn fat
  • Decreases cholesterol
  • Slows cell aging and helps grow stem cells

*High NNMT levels affect the body’s ability to metabolize appropriately, untreated can lead to type-2 diabetes and obesity

Another significant change for me is that I no longer feel like I’m as ravenous or sometimes even weak between meals.

I assume it’s because my body has another source of fuel.

And I’ve noticed disappearing fat that I’m not sad about parting with!

My Dose: 1/4 cap in early morning and sometimes again at noon. At this rate, the bottle is going to last a long time!

  • It has a very strong taste, you will need to put the 1/4 cap into another capsule – as always, it is ok to combine any peptide with others in the same capsule.

When I skip a day, I notice a drastic difference.

It could cause difficulty sleeping if you take too much or too late in the day – I have taken it at 5 pm and that was not a good idea!

In USA — Limitless purchase here. 20% off with code: QUALITY Quantity: 60 caps

Or

Biolab link to purchase is in the title or here. Coupon: RESTORE Shipping to USA is over $45 😔 quantity: 30 caps


11. DSIP (Delta Sleep Inducing Peptide) nasal spray

DSIP helps me sleep more efficiently / deeper and feel more rested in a shorter amount of time!

At the right dose it can completely stop my night waking and trips to the bathroom.

It binds to receptors in the brain linked to sleep and relaxation.

By increasing the production of GABA, it slows brain activity, induces relaxation, and promotes deeper sleep.

It can also lower inflammation in the sleep center.

• We have a comprehensive DSIP blog post (here)

Video:

It originally did not help me fall asleep but when I switched to the Limitless Brand I noticed that I was actually falling and staying asleep more than with the Biolab Brand.

I’m not sure if this is a difference in product or perhaps a difference in the amount that is coming out of the sprayer.

They are both listed as 50 mcg per spray.

Typical dosing is 100-150 mcg but even 2.5 sprays of limitless (125mcg) left me noticeably groggy the next morning.

My Dose: 1 spray 1-2 hours before bed.

1 spray – Doesn’t help as much with decreasing initial time to fall asleep & I still briefly wake in the night but fall back asleep

2 sprays – I fall asleep more quickly and don’t wake at all.

Experimentation is key!

Purchase here from Biolab: https://biolabshop.eu/peptides-for-regeneration/202-dsip-spray-5mg-.html

Coupon code: RESTORE

•••

(Limitless also sells DSIP, and I have switched to theirs, see below)

https://www.limitlesslifenootropics.com/product/dsip-spray/

Code: QUALITY for 20% off


12. Oxytocin – nasal spray

This spray quite noticeably decreases my daughters social anxiety.

Every time we use it I’m amazed it’s as effective as it is.

It’s well studied and often used in the autism community and I like having it on hand for my daughter prior to social activities.

Her Dose: 1 spray, 30 minutes before effect is desired. (Not more than once a day)

I’ve read that using it every day decreases effectiveness. We use it infrequently and have remarkable results each time.

I’d aim for less than 3x per week but that is just anecdotally.

Biolab Purchase here: https://biolabshop.co.uk/peptides-for-regeneration/113-oxytocin-spray-10mg.html Discount code: RESTORE

Limitless also sells Oxytocin (here) each bottle is 5mg so you will want 2 sprays per dose.

Limitless Coupon Code: QUALITY for 20% off

Benefits of Oxytocin

Enhances social bonding: Promotes trust and emotional connection in relationships.

Reduces social anxiety: Can ease stress in social situations

Improves emotional recognition: Could help individuals with autism better interpret social cues and emotions.

Supports stress regulation: Lowers cortisol, aiding relaxation in social interactions for those with social challenges.


13. Epithalon – Pineal Gland, nasal spray

A synthetic peptide based on a natural peptide in the pineal gland – epitalamine.

We know from PinealPep (above #8) how the pineal peptides are master bioregulators.

They’re considered essential for longevity, overall wellness, and regulating circadian rhythm.

You would purchase this as an alternate to PinealPep if you prefer a nasal spray.

Biolab Purchase here: https://biolabshop.eu/peptides-for-regeneration/105-epithalon-spray-10mg.html Discount code: RESTORE


Pineal gland bioregulators – in capsules

(links take you to their section in this post):

You only need one of them ☺️


Reconstitution

When you order a nasal spray, you will receive everything needed to reconstitute them and instructions.

We have videos and written instructions (package inserts) for you on this page:


14. P21 – nasal spray

P21 is a synthetic version of one component of Cerebrolysin (brain peptide).

There have been some remarkable gains reported when using this with children who have autism (search our group for some reports).

I gave it to my daughter and didn’t notice a difference… BUT she was already taking CogniPep (above) which is more than one component of Cerebrolysin plus vessel bioregulators – making it inclusive of P21 and more comprehensive.

I believe P21 can deliver a brain boost on its own, but we did not see additional improvements over CogniPep.


Nasal Sprays – PRO / CON

• I prefer capsules whenever possible because you can much more easily adjust the dose – down or up.

If one spray is too much, you would need to dilute the bottle

• A benefit of sprays is delivery of the peptides very close to the brain.

You can see from the description that P21’s benefits are similar to other brain peptides.

The only side effect we saw was drowsiness for about 30 minutes after dosing which is indicated as a possible side effect.

Worth trying if you like nasal sprays and aren’t taking any other form of Cerebrolysin.


15. Selank – anti anxiety, nasal spray

Selank spray is very calming to my daughter. It significantly decreases both anxiety and fixation on ideas.

I’m often surprised at how well and how quickly (5-10 minutes) it works!

If I am awake in the night and can’t sleep, it stops my restless mind and I can easily fall back asleep. (It does not itself cause drowsiness)

It also helps completely eliminate headaches and period cramps in our household… within minutes!

We made a video with a deeper dive into Selank and you can watch it here

Research indicates Selank can:

  • Reduce anxiety without sedation or dependancy
  • Affect the binding of GABA to its receptors
  • Modulate the balance of dopamine and serotonin, promoting a sense calm and of well-being
  • Alter the expression of genes involved in stress response pathways, improving ability to manage stress
  • Positively influence brain-derived neurotrophic factor (BDNF), a protein linked to cognitive health.

Also intriguing is its potential to support overall wellness and the immune system.

By modulating cytokines, inflammation is reduced and a cascade of improvements can result (even fewer stomach ulcers).

This article is an excellent summary of Selank benefits with research.

Our Dose: 1 spray as needed / morning or evening (or both!) – it can be used anytime of day. It works rapidly (under 10 minutes).

Some use it 2-3x per day

•••

Biolab purchase with coupon code RESTORE here: https://biolabshop.eu/peptides-for-regeneration/111-n-acetyl-selank-spray-5mg.html — it is NOT Amidated.

***Limitless sells Selank and Semax and we use their brand because it is also amidated. (see #17 below)

As discussed in the “No Cap” section above, the Acetylated and Amidated version works better than standard Selank.

The addition of an acetyl group and an amide group enhances its stability and bioavailability compared to standard Selank.

There’s also a new version (sold at Limitless only) called Adelank. I’m going to order it next time so please don’t buy it all 😌

Image from Kona Health

16. N-Acetyl-Semax – brain & body boost, nasal spray

Semax is an analogue of adrenocorticotropic hormone (ACTH).

• ACTH is released under conditions of stress increases cortisol production from the adrenal glands.

• Some say the effects feel similar to “psyching yourself up.” I would agree and liken it to listening Van Halen’s “Jump” or “Right Now” while eating some sugar 🎸🤘🏼🍫 (DIY Semax idea?)

I gave it to my daughter and she began running around the house. Her attention and patience reduced to zero.

Quickly, I remembered Semax and Selank are iften used together as a 50-50 combo.

I gave her 1 spray of Selank and within a minute she was both calm and focused. She sat down, opened a book and started reading!

Semax is known for visual tracking benefits so it could have been a factor. But she will read calmly when she just takes Selank also.

I could not believe the dramatic shift from normal to supercharged to calm/focused.

Our kids do not need to be psyched up, so Semax is a no from us.

We can get the same brain benefits from CogniPep and a little Selank as needed.

There’s an updated version, ADAMAX you can buy all you want, we won’t be needing it 😌


Storage of peptides prior to reconstitution

You may wonder what to do with the tiny glass bottles of powder for the nasal sprays if you’re not using them immediately.

I keep mine in the freezer. (Capsules of course can be kept at room temperature unless they say otherwise which is rare)

• Biolab instructs to store vials at 32-40 degrees

• Limitless instructs to freeze them

I prefer to follow the Limitless protocol for all of ours.

After reconstitution all liquid peptides need to be stored in the refrigerator.


Limitless Biotech

•••
Discount Coupon at Limitless:
QUALITY – 20% off
stackable with other promotional discounts

Coupon Code QUALITY For 20% off

The only products I have purchased from Limitless (so far) are nasal sprays.

Their company is in the USA, is 3rd party tested, has customer service you can usually reach and a good tagline – “Life is Short. Live Limitless.”

17. N-Acetyl-Selank Amidate, nasal spray

Semax and Selank might be the most remixed peptides of all time 📻

Each one promising to be better than the last.

For us, this version works better than standard Selank (above).

Buy it from Limitless here: https://www.limitlesslifenootropics.com/product/n-acetyl-selank-amidate-10ml/

Discount code for 20% off: QUALITY

Acetylation and amidation are important.

See the “No Cap” section above for a more detail on how they’re a closer match to our own natural peptides and have improved bioavaiability.

My daughter uses this version daily and it’s been transformational!

Limitless also sells: Adamax / Adelank Combination Pack – nasal sprays


18. VIP – Vasoactive Intestinal peptide

If you struggle with immune system stimulating products or have IBS (-C or -D), RA or MS, this peptide may be the one for you.

VIP is produced by our neurons and cells and is present in most organs including:

CNS, heart, lung, thyroid, kidney, urinary and gastrointestinal tracts, genital organs and the immune system.

Some of us don’t produce enough VIP.

If we don’t, supplementing it can be beneficial.

Studies have shown even a 20% reduction in brain VIP caused learning impairment especially in memory acquisition!

Impact on the Immune System

VIP promotes the development of Th2 cells and inhibits Th1 differentiation.

This shift can be helpful for people with Th1 dominant pro-inflammatory conditions.

Note: If you are not Th1 dominant, have mold illness, cancer or an ongoing infection – including viral, VIP is not the peptide to take.

However, for people who need to foster a Th2 response, it can be difficult to find treatments and VIP is an option.

Read more in: The Neuro peptide VIP: Direct effects on immune cells and involvement in inflammatory and autoimmune disease diseases

In this study, Vasoactive Intestinal Polypeptide Plays a Key Role in the Microbial-Neuroimmune Control of Intestinal Motility – ScienceDirect, they showed it can treat both IBS-C and IBS-D.

Some of the benefits:

  • Neuroprotective
  • Anti-inflammatory – inhibits production of pro-inflammatory cytokines
  • Meditation of Immune T cells (favoring a Th2 response)
  • Promote GI health & microbial balance
  • Brain health: regulate circadian rhythms and sleep-wake cycles.
  • Hormonal regulation: help correct imbalances
  • Pulmonary health: calm respiratory conditions – asthma and pulmonary hypertension

While VIP can improve CIRS patients’ symptoms for some time under the right conditions (i.e., low TGFb) by causing paralysis to parts of the immune system, caution should be used if using VIP at any time for extended periods or in anyone with a chronic infection.” – Dr Holtfoft’s CIRS Book

I use 1 spray only as needed, not daily or even weekly, I’m still experimenting with it to see how it affects my system.

• Biolab also sells VIP (here)


Limitless also offers many other peptides that are reviewed on other sections – for example:

DSIP (spray)

For us, Limitless DSIP works better than Biolab.

I purchase the 99+% lyophilized option but either one should work.

https://www.limitlesslifenootropics.com/product/dsip-spray/

Limitless prices can be higher but they offer larger discounts, 15% off with coupon QUALITY, free shipping and it’s an easy transaction experience! (Priceless)

Oxytocin (spray)
Epithalon Capsules (pineal gland)

Another entry in the Pineal gland bioregulator category. Choosing one of these for your peptide stack is essential!

5-AMINO-1 MQ (Longevity, Fat cell metabolism & energy)

Priced higher but for 60 capsules (Biolab is 30)

See above for info

N-Acetyl Larazotide Amidate

Is available from Limitless here: https://www.limitlesslifenootropics.com/product/n-acetyl-larazotide-amidate/

They recently added the Amidate which Biolab does not have, so we are going to try it!  — UPDATE: it works better!

See our review

The coupon- QUALITY is for 20% off (anything) which you can stack with a company sale but I haven’t seen it included in featured “sale” products. 


Click here to go back up to the Contents List


Bioregulators – Peptides à la carte!

Bioregulator peptides help optimize performance of organs of your choice and may be taken together.

These ultra-short peptides are small enough to enter the cell nucleus, interact with the DNA, and instruct our genes.

They stimulate the expression of youthful genes and suppress the expression of age and illness-associated genes.

The result is a rejuvenation and restoration at a cellular level in specific tissues, glands, and organs – and widespread health benefits!

“Peptide bioregulators have rapidly gained
recognition in scientific circles.. They are often described as the future of medicine due to their unique
ability to interact with our DNA and fine-tune cellular processes.

Unlike typical medicines, they don’t just treat symptoms; they engage with the root of health issues – our cells and genetic code.” –Khavinson

Update! 2025 – We have a New Guide & Video to learn all about Bioregulator Peptides

Post: Inside and out, Peptides healed my body! DIY Bioregulators: Step-by-Step Guide


Click for more on each and pdf

📝 See also our page: How to create your Combination Bioregulator Protocol – 12 Examples

All Bioregulators we have tried with good results!

Because of their limited action, they can be taken with confidence that you’re not “doing it wrong” or will react negatively.

They simply allow our body to reach its optimal state of function.

Accordingly, their effectiveness is limited to our personal best.

For example, I haven’t become Einstein, but I do feel my brain is working as well as it ever has in my life

Some say to expect around a 30% improvement from bioregulator peptides.

I say, let’s all find out what our best is!


Some Integrative Peptides products (above – ThyroPep, CogniPep & PinealPep) contain combinations of bioregulators and I will note how these differ from the à la carte versions below.


VitaStream

In this photo, see my highlighted labels for the corresponding organs:

Discount Coupon at Vitastream:
BIOREG10 for 10% off
Free shipping

I have purchased more bioregulators than I should probably admit. 🙈

In my defense, who doesn’t want ALL of their organs to function optimally?!

To save others from starting their own peptide warehouse, I’ll let you know which ones we like the best.

I generally use only a portion of the capsules (not “full” doses) and my dosage is indicated for each.


Natural or synthetic?

I was originally overly invested in which was superior.

They are both effective and a positive about synthetics is the lack of taste.

Some of them don’t come in a synthetic option.

Focusing on which peptide best suits your health need is more important.

If you need to avoid porcine, synthetic is the option you will want.

Lingual or capsules?

Sublingual peptides are absorbed directly through the mucous membrane of the mouth, which promotes faster penetration of peptides and accelerates their action.

At VitaStream, bioregulators are sold as either liquid (sublingual) or capsules. We have tried both.

The linguals must be kept refrigerated.

We find that the capsules, with the powder used sublingually or as part of a larger capsule you make are the best value and convienence.

Combo or Individual?

VitaStream offers combo products that contain 3 peptides in one capsule. Most of them contain thymus peptides so we haven’t tried many.

Some contain lactose – if you need to avoid, be sure to check labels.


Master Chart of Bioregulators

This helpful list is handy but I don’t think you need as many as it may seem, so read on for thoughts about which ones are essential!

Which Brand to choose?

Khavinson peptides (VitaStream) and Natures Marvels (NM) are interchangeable.

Vita Peptides, made in the USA are more potent and a better value than either of the two above. They are our preference.

The links I’m giving are to the specific products I use, you can search VitaStream for lingual or combo products.


19 & 20. Lungs – Taxorest, Chonluten & LunGuard

Links above are to purchase & Coupon: BIOREG10 for 10% off.

My journey with bioregulators began when Dr. Holthorf suggested Taxorest for asthma. While KPV was keeping it under control, I wanted to take a break from KPV.

Taxorest is the naturally derived peptide.

I switched to Chonluten, synthetic because it seems to work faster and it has no taste.

I now use the latest release LunGuard it’s the same peptide as Taxorest just a bit more potent and made in the USA

Coupon: BIOREG10 for all the versions

(LunGuard does also have a taste but I still use it under the tongue)

My Dose: I took about 1/5 of a capsule under the tongue several times a day for approximately 6 months.

I still take 1/5 capsule once a day, sometimes more.

Recently, I added it to my daughter’s stack because she was coughing after being sick. It helped!

In reference to the 30% improvement estimate, I feel this peptide delivered exactly that.

Not only are my lungs asthma free, they have a capacity I did not know was possible – I understand now how people can sing!

Interestingly, when my lungs improved, I started having flashbacks to riding my bike and hiking all day in the woods as a young child – before I developed allergies.

I know that sounds unreal, but it’s as if my body remembered the feeling and my brain associated it.

For Asthma:

The combination of both KPV and a Lung bioregulator is be best for someone just starting to treat asthma.

After a few months I was able to switch to just the bioregulator and then take breaks from that too.

•••

“Supports lung function by regulating bronchial mucosa and improving metabolism. Ideal for those with chronic bronchitis, asthma, and pulmonary disease. May aid recovery from chronic heart failure when combined with the Heart and Blood Vessel Bioregulator.”


21 & 22. Blood Vessels – Ventfort / Vesugen

(Natural / Synthetic versions)

Links above are to purchase & Coupon: BIOREG10 for 10% off.

I mentioned the importance of Vessel Bioregulators in the CogniPep section.

These pair well with and enhance the function of all other peptides and bioregulators.

Because they can help more blood reach the brain, I also consider them critical in the stack that ended my lightheadedness and dizziness – more about this is below.

They can help increase blood flow to other organs as well, of course!

Our Dose: 1/4 cap Ventfort 2x per day

“Supports blood cell function by promoting vascular wall health and regulating metabolism. They help manage cholesterol and lipoproteins, reducing the risk of vascular issues.”

23 & 24. Central Nervous system – Cerluten / Pinealon

Links above are to purchase & Coupon: BIOREG10 for 10% off.

These are respectively natural and synthetic Central Nervous system bioregulators.

Pinealon has been more extensively researched, so we will center the discussion on it. 

It is not the Pineal Gland bioregulator – it’s name has led to the confusion of many people!

Pinealon’s neuroprotective properties are well supported. From this review of research literature you can find links to many studies.

It’s known to:

  • Activate gene expression involved in maintaining neuronal functional activity
  • Normalize behavioral responses and improve memory issues.
  • Prevent the loss of neuronal dendritic spikes in Alzheimer’s
When searching for scientific studies, Pinealon is also referred to as EDR peptide (Glu-Asp-Arg)
  • Reduce excitotoxicity
  • Diminish mitochondrial dysfunction 
  • Inhibit the activation of extracellular matrix metalloproteinases, thus increasing the viability of the neurovascular unit in the brain

• In 72 patients with traumatic brain injury, it led to improved memory, reduced duration and intensity of headaches, emotional balance, and enhanced test performance.

It was the perfect starter CNS bioregulator for us!

Our Dose: Lingual, 2-3 drops in the morning. We typically used it for several days (up to about 5 days) and then took a 1-2 day break. It can be stimulating if you use too much.

For capsules, 1/4 cap would be the equivalent.

*You can pair either of these CNS / brain bioregulator peptides with an above blood vessel bioregulator for even better results (it will help them reach deeper into the brain)

Vesugen is the synthetic option (#2 above)

Synthetic alternative to CogniPep: Pinealon + Vesugen

This gives you 2/3 of the bioregulators in CogniPep – they are not acetylated or amidated (not as bioavailable) so I would only use this option if you cannot have porcine. But, they do still help, and are recommended !

Product info from Linguals

25. Pineal – Endoluten (lingual)

Link above is to purchase & Coupon: BIOREG10 for 10% off.

We’ve talked a lot about the importance of pineal gland bioregulators, so in the interest of saving space, please see here if you skipped directly to this section.

Our Dose: 1/4 cap or 2 drops (lingual) in evening

“This pineal gland bioregulator supports the neuroendocrine, immune, and cardiovascular systems, enhances melatonin production for better sleep, and promotes telomere length (anti aging) and overall gland health.”

26. Stomach – Stamakort

(Now use Stomek, Vita Peptide, search at above link)

Link above is to purchase & Coupon: BIOREG10 for 10% off.

As a person with lifelong IBS and on my break from KPV, I thought this would be a good one to try next.

I like it! I can’t say that I “noticed” anything other than my stomach feeling better.

Our Dose: 1/4 cap per day in the morning

* I originally took a approx 1/6 cap before every meal (combined with Pancreas).

“Supports stomach health by normalizing digestion and helping prevent gastric ulcers, polyps, heartburn, belching, and a heavy stomach feeling.”

27. Pancreas – Suprefort

Link above is to purchase & Coupon: BIOREG10 for 10% off.

We take this one because it combines well with Stomach and Liver and we take both of those

Our Dose: 1/4 cap per day – morning

Helps regulate pancreatic enzyme activity, potentially lowering blood sugar in diabetes and supporting pancreatic tissue recovery.

28. Liver – Liverra

Link above is to purchase & Coupon: BIOREG10 for 10% off.

Ovagen is synthetic version

Struggling to detox is not unusual for my daughter and at times her skin will be very slightly yellow-ish.

Liverra, combined with the kidney bioregulator (below) visibly helped her detox and she was back to normal color about 2 days!

Our Dose: 1/4 cap per day

It also helps with hepatitis, fatigue, and digestive issues. It may benefit those with atherosclerosis, diabetes, and obesity.

Combining stomach, pancreas and liver can provide more comprehensive GI support.

29. Kidney – Pielotax

Now use Renolux – search for it at same link

Link above is to purchase & Coupon: BIOREG10 for 10% off.

Link above is to purchase & Coupon: BIOREG10 for 10% off.

This one is also great for detox!

The kidney removes toxins and waste, maintains electrolyte and fluid balance. Important for people with POTS.

Our kidneys also produce hormones that regulate blood pressure and control the production of red blood cells.

I take it in combination with other peptides to help my blood production and eliminate my dizziness. (See bone marrow below)

Our Dose: 1/4 cap per day

“Also helps lower uric acid and urea levels and manage more severe kidney conditions.“

30. Bone Marrow – Bonomarlot

Link above is to purchase & Coupon: BIOREG10 for 10% off.

I believe this was essential to helping stop my lightheadedness and dizziness. I am not clinically anemic but felt the symptoms so I decided to try to further boost my blood volume and flow to the brain.

I already was taking 1-2 packets spatone liquid iron and 1/2 cap blood vessel bioregulator. (These were not enough)

I added:

• 1/4 cap bone marrow bioregulator

• 1/4 cap kidney bioregulator

• 5mg Vinpocetene (in morning – to increase blood flow to the brain).

The combination worked! I no longer have any lightheaded or dizzy feelings, which almost feels like a miracle considering how frustrating it was for more than a decade.

“This bioregulator helps balance bone marrow function, benefiting individuals with excess red blood cells or anemia. It supports bone marrow regeneration, boosts red blood cell production, and promotes a healthy hematopoietic system.”


A note on Vita Peptides from VitaStream

Three of the below peptides are from VitaStream’s new Vita Peptides line. (Adrenact, Endocron, Collacell)

They contain the same peptides as the Khavinson line but a larger active amount per capsule and larger quantity of capsules in the bottle. They are made and lab tested in the USA.

Most are available in both 30 and 60 capsule options

You can use the same coupon “BIOREG10” at VitaStream and they have free shipping

VitaStream assured me Collacell is for skin elasticity – this is a misprint, the rest is accurate 🙂

31 & 32. Adrenals – Glandokort & Adrenact

Links above are to purchase & Coupon: BIOREG10 for 10% off.

Overwhelm and emotional lability are signs our adrenals need some care. This bioregulator is an excellent choice if you’re exhausted, unmotivated or battling any illness.

We use it every morning and my dose is in the below section.

If your adrenals are in serious need of help you could also add the glandular adrenal cortex extract.

“Supports adrenal gland function, helping to balance stress hormones like cortisol, adrenaline, and noradrenaline, which may improve energy, stress levels, and metabolic health. It may also aid the endocrine system, especially in older adults.”


33. Pituitary – Endocron

Link above is to purchase & Coupon: BIOREG10 for 10% off.

One of my most favorite peptides!

Despite the name, it is not related to endoluten or the pineal gland.

The pituitary is a small but powerful gland at the base of the brain, regulating many critical body functions, including metabolism, growth, and the reproductive system.

•••

It’s an important bioregulator for anyone concerned with hormone production and extremely valuable for peri & menopause symptoms.

I started taking it when I wanted to try a break from KPV and was concerned about how my mast cells might react.

Choosing endocron as a possible stand-in was based on a theory that the HPA axis (hypothalamus-pituitary-adrenal) can regulate allergic inflammation.

I take:

Adrenact (adrenals) – 1/4 cap in morning only

Endocron (pituitary) – 3/4 cap total, spread through the day

Hypothalamus glandular – 1/2 cap per day morning only

Update – I switched to the VitaPep’s brand new Hypothalumus bioregulator (Hypotalen) and I love it!

Please see my Bioregulator Guide for more info on Hypotalen and all of the 26 Bioregulators

This HPA bioregulator combination definitely seems to work to keep my allergies extremely low ~ not as effectively as KPV (which for me results in total elimination) but surprisingly well!

It could have a positive imact for anyone with suspected HPA dysfunction.

Causes of HPA axis dysfunction could result from genetics, medications, early-life environment (childhood trauma), and current life stressors.

“Some of the general symptoms of HPA dysfunction include:

  • Feeling irritable
  • Frequent illnesses
  • Difficulty coping with stress
  • Feeling unexplainable tiredness
  • Feeling overwhelmed
  • Experiencing an exaggerated response to stress” (Source)

In other words. We could all have this!

I have seen improvement in every item on the list while taking these peptides.

My daughter is also showing a much improved response to stress.

Endocron is designed support:

• the endorcine system • healthy metabolism • sleep patterns • mood • cognitive functions • a healthy response to stress •


34. Thyroid – Thyreogen

Link above is to purchase & Coupon: BIOREG10 for 10% off.

I used this bioregulator before Integrative Peptides released Thyropep but I didn’t notice any real change. 

I took approx 1/2 cap per day, which is the same quantity I took when I started ThyroPep (above).

In summary – ThyroPep drastically improved my life, this one didn’t.

“Helps treat both hyperthyroidism and hypothyroidism and may prevent autoimmune thyroiditis. It can be combined with the Blood Vessel Bioregulator for added support.”


35. Heart – Chelohart

Link above is to purchase & Coupon: BIOREG10 for 10% off.

I took the lingual version of Chelohart for a few weeks.

It may have helped with my long COVID related racing heart but I think that was primarily driven by central nervous system dysregulation.

If I develop a heart condition someday, I would absolutely take it and I would use 1/4 – 1/2 cap per day.

“Supports heart function and may help with conditions like hypertension, myocarditis, AFib, coronary artery disease, and heart failure.

It also helps reduce stress for better heart health. Pair with bioregulators for blood vessels or liver for full cardiovascular support.”

36. Muscles – Gotrattix

Link above is to purchase & Coupon: BIOREG10 for 10% off.

This did not give me a muscular physique without working out – go figure! 

I took the lingual version for one course and didn’t continue. I’m sure it could work better for someone actively trying to develop muscles.

There are studies showing muscle bioregulators are quite effective.

Also, for building muscle, you may be interested in 5-AMINO-1 MQ (above)

“Supports muscle function, enhancing physical performance and adaptability during intense training. It helps restore muscle performance, improves mobility, and regulates oxidative processes.”


37. Ovaries – Zhenoluten

Now, OVALIS – search at Link above is to purchase & Coupon: BIOREG10 for 10% off.

See Our page https://diaryofrecovery.com/over40 for in depth review!

They can reduce common peri & menopause symptoms.

Even a very small quantity is effective – I take 1/4 cap.

It is also said to be useful for PMS / PMDD but we don’t have experience on using it for those.

The effects og this bioreguator have increased with time (2 months).

“Supports ovarian function by regulating estrogen and progesterone production. It may help alleviate symptoms of hormonal imbalances, including those during menopause and perimenopause, such as hot flashes, low libido, and menstrual issues.”

• Also for hot flashes – I strongly recommend Apiginen and I wrote about it here.


38. Eyes / Retina – Visoluten

Link above is to purchase & Coupon: BIOREG10 for 10% off.

I’ve only usit for a scratch on my cornea. I also used red light therapy which is think helped more, at least more immediately.

I’m sure it’s beneficial but I don’t have any of the eye issues it helps with.

“Retinal damage from conditions like diabetic retinopathy, myopia, and age-related macular degeneration. It can also address damage from hypertension, kidney issues, diabetes, smoking, or alcohol use.”


39. Bladder – Chitomur

Link above is to purchase & Coupon: BIOREG10 for 10% off.

I have had chronic cystitis my my life but it’s managed completely with a low oxalate diet.

I tried this to see if it would make my bladder less sensitive, but I also don’t eat oxalates, so I didn’t notice too much of a difference.

It could be helpful for others though!

“Supports bladder control and flexibility by regulating metabolic processes and reducing oxidative stress. It may benefit conditions like overactive bladder (OBS), BPH, chronic cystitis, and reduced urine flow.”


40. Cartilage – Cartalax

Link above is to purchase & Coupon: BIOREG10 for 10% off.

I took this sporadically in an attempt to help my joints.

Collacell below helped me more.

I took about 1/4 cap per day.

It’s a bioregulator that becomes more important as we age.

“Supports cartilage health by regulating tissue metabolism, potentially reducing joint and spine issues, pain, and improving mobility.

Ideal for conditions like osteoporosis, osteochondrosis, or osteoarthritis”


Collagen Bioregulator

Bonus #41 Skin and joints – Collacell (new!)

Link above is to purchase & Coupon: BIOREG10 for 10% off.

Also – all VITA PEPTIDES bioregulators are 15% off until 8/18/25 with the code: VITAPEP15

You may not believe this because I almost couldn’t but the texture of my skin was smoother, softer and feeling more elastic after using this bioregulator for only 2 days!

After two weeks, I noticed certain areas slightly but noticeable lifted – cheeks, upper lip, chest. My skin tone seems to be evening too (less freckles)!

After 4 weeks it’s gravity reversing effect above eyes, at cheekbones and tightening of my skin everywhere is undeniable. It’s the most effective beauty product I’ve ever used!

Not to be confused with taking collagen peptide powder (broken down collagen), collagen bioregulators stimulate the body’s production of collagen and elastin.

Collagen bioregulators have performed very well in studies and are shown to:

  • Support and maintain skin, joint, muscle and overall connective tissue health
  • Can help improve skin elasticity and reduce the appearance of wrinkles 
  • Can also help regulate hormonal balance and improve cellular metabolism

My Dose: The powder from 1 full capsule divided several times through the day, under the tongue

It has no taste and I use it morning through night no side effects.


42 and Beyond!

As new Vita Peptide Bioregulators are announced, we are testing them!

ALL future Bioregulator updates will be added to our Guide (current total is 26 organs):

The two most recent that I ordered (June 2025) are — Gastric Mucin (excellent for acid reflux) and a Bile Complex.

You can find links to them as well as other new options in the Vita Peptides category at this page:


Any tips for organizing / taking multiple peptides?

The method I’ve found easiest is to keep a small quantity of capsules out of their original bottles.

To fill one larger empty capsule, I use a capsule holder and pour in the desired amount of each peptide.

For peptides as needed or carrying through the day:

• Use a small pill container.

• Open the appropriate capsule and sprinkle a little under the tongue.

Using many different bioregulators and peptides isn’t difficult if you find a system that works for you!
This is from Targ and fits the bottle perfectly! A push button pill box is the easiest for us!

Combining:

All of them can be combined except there are instructions not to take adrenal and pineal – endoluten / epithalon (circadian rhythm) peptides together.

This makes sense! I do take them on the same day (am/pm) but not “together.”


My Current Peptide Stack 

Links direct to section in this post.


  • ThyroPep – upon waking, empty stomach

MORNING (approx 1/4 cap each combined in 1 larger capsule)

VARIOUS TIMES — Divided doses several times per day, powder under tongue: Skin elasticity (Collacell total 1 cap), Muscles (GoTratix total 1/2 cap)

EVENING (1/4 cap each)

As needed (sometimes less than daily): KPV (microdose 1-2x /day, toothpick size amount)

My Daughter’s Peptide Stack: 

MORNING

EVENING

~ As needed: Oxytocin spray


Coupon Codes

Here are coupons for each of the brands we use. They are unlimited in use.

Integrative Peptides: SAVE10

Biolab: RESTORE

VitaStream: BIOREG10

Limitless Life: QUALITY (20% off, stackable always — and free USA shipping for a limited time with this code only


Click here to go back up to the Contents List


We made it to the end! 

Without some of these peptides, I’m not sure I would have! 

Final thoughts ~

• Buy quality peptides from trusted brands

• If you have the right peptide a little goes a long way – start dosing low, you can always take more

Space apart introductions – although many sound attractive, this isn’t speed dating! Our bank accounts want us to be sure which ones warrant repeat purchasing.

• Please let us know which peptides are in your toolbox.

We love hearing everyone’s success stories!

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I hope you too find a path to everything you search for on your peptide journey!
Thank you for coming along on ours 🤍

Need personalized help? Our digital mind tool – highly acclaimed! Is here: https://diaryofrecovery.com/dm


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14 thoughts on “We tried 40 peptides in 1 year – our reviews and top picks!

  1. Hi there! Wow! I thought I had tried a lot of peptides, but there’s a few on here I had never heard of. Excellent resource! I just wanted to say, I’m surprised to see your daughter is taking pineal products like endoluten (epitalon/epithalamin) because I was told that one specially isn’t safe for children under 18 because it can lengthen telomeres and delay puberty.

    1. Hi! I’m working on a post for the kids group too and will be mentioning which are safe / not safe – my daughter is 18 so its ok for her and I also don’t plan to give it forever but wanted to try it for her sleep issues 🙂

      There is a similar issue with taking melatonin and no one really talks about it.

      I didn’t figure kids would be taking the anti aging peptide but I should specify it in this post too – Thank you for pointing it out ☺️

      1. Hi Rebecca! Is there a post for kids on the bioregulators peptides? I saw that Pinealpep is not recommended. TIA!

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