Peptide Dosing Information for Capsules and Sprays

The below doses work well for us and others, they are on the low side – always tailor to your own needs!

This is not medical advice.

• Peptides on this page are all non-prescription and are available from stores on this page.

• For kids or extremely sensitive, people typically reduce amounts even further.

• Mixing in food is ok for powder from any capsule (if sublingual or swallowing capsules aren’t an option).

• Some people may want to take or experiment with larger doses than listed here.

• As peptide use continues, genetic changes happen and many peptides can be tapered, paused or switched to micro-maintenance dosing. 1-3 months approx, timelines vary.

The reason we don’t follow what the boxes / bottles say is because even the peptide manufacturers have explained that they “just needed to put something on the bottle – and everyone should experiment.”

This page is a result of reports from our experiments and those of many people in our groups — yes these small doses can and do work, very well!

• Acute Illness protocol is at end of this page.

All doses are approximate

• Time of day?

When new, it’s best to start earlier in the day and finish by late afternoon – Until you are familiar with effects. (Except sleep peptides)

• Pulse dosing?

Typically this done because a peptide works too well or is too potent (why we use small doses).

But if after an extended time, you notice one isn’t working like it used to, you may be experiencing cell receptor desensitization.

When a signal is sent continually, some cells dial down their receptors which can make certain peptides less effective.

This is very rarely reported in our group, but if you notice it, you may want to take a break (approx 3 days)

Peptides on this page can all be combined with one another.

For Personalized help:

Learn more about how it that can help you with peptides, supplements, lab reviews and so much more!

Integrative Peptides

KPV – antimicrobial, anti-fungal, anti-inflammatory, calms mast cells

  • Day 1 – Begin with 1/20th capsule (small sprinkle) to test
  • Days 2-10: Aim for 1/10th capsule 2-3x per day. Less is ok! Either under the tongue or inside another capsule.
    • If you have any type of die off symptoms (headache, irritability, GI upset..) pause and consider binders – die off info here.
  • Continuing: Increase until you reach max: 3/4 to 1 capsule total per day (still divided doses & if you never get there it’s ok!)
  • Decreasing: When your symptoms are resolved, try decreasing slowly.
  • Maintenance: Keep a microdose daily (avoids experiencing die off) or pulse use as needed.
  • Some people notice acid reflux if prone to it, if so – take it only inside another capsule.
  • See this post for important KPV dosing details

TB4 Frag – tissue healing

  • 1/4 capsule, 1-3x per day (as needed for healing – can pulse at any schedule)

ThyroPep – thyroid (all types)

  • 1/2 – 1 cap in morning, first thing

Cognipep – cognition

  • 1/8 – 1/4 cap or less, AM only, skip days as needed if it gives too much brain stimulation or energy.  Some use it just one day per week! Others do up to 5 days on, 2 days off, taper as you progress.
    • 1 small sprinkle, 1-3x per week maintence dosing seems right for many.
  • CerebroPep – follow same dosing

Remember: Brain healing is hard work!

If you take a larger dose, your brain will be working so hard on healing that gains may be masked, unrealized until several days after you take a break.

Epitalon – Pinealon Spray – liquid blend of above and below

  • Transfer to eye dropper bottle and use 1-2 drops in the morning.

PinealPep – anti aging, endocrine & circadian rhythm support

  • 1/8 – 1/4 cap in daytime or evening, typically for over 18 only because of telomere lengthening. Experimenting can be required with timing because often pineal gland bioregulators are taken in the evening but this one also contains 1/4 CerebroPep which could be stimulating for some.

Thymogen Alpha 1 – immunity

  • 1/4 cap, 3 – 5x per day during acute illness.
  • If you’re not Th1 dominant you may use it more regularly to boost immunity and shift away from Th2 dominant autoimmune issues. (See this post for more info).

Can’t weight – weight loss (via appetite control)

  • 1/2 – 1 capsule per day
Bioregulator Peptides: Adrenals • Bile • Bladder • Blood Vessels • Bone Marrow • Brain / CNS • Cartilage • Collagen • Gastric Mucin • Heart • Hypothalamus • Kidneys • Liver • Lungs • Muscles • Ovaries • Pancreas • Parathyroid • Pineal (Endocrine) • Pituitary • Placenta (whole body) • Prostate • Retina / vision • Stomach • Testes • Thymus • Thyroid

Organ Specific – Bioregulator Peptides

When you first begin a bioregulator peptide, sometimes you can see initial improvement within a couple of days, but expect 1-2 weeks to see the most changes.

Vita Peptides (capsules in bottles) – 50% stronger

Khavinson (in boxes or linguals) from Vita Stream, Natures Marvels – less potent: you may want to increase slightly

– We combine up to 10 together, there is no rule.

– Use powder under tongue or inside another capsule for ones with a taste (all can go in same capsule).

Common Schedule

You can use more, organ bioregulators (except brain which can be stimulating) are generally very forgiving in dosing:

  • 1st Month ~ 1/4 cap, 2 or 3x per day
  • 2nd Month ~ 1/4 cap, 1 or 2x per day
  • Beyond ~ pause / cycle as needed. Ok to continue at low dose.

Note: Gastrogen can cause slower motility as mucin layer thickens. Use less if you have issues.

Exceptions – AM or PM specific (once a day)

• AM — Adrenal, Pituitary, Hypothalumus (hormonal production), CNS-Pinealon (can be stimulating)

For Integrative Peptides Brain Bioregulators (eg. CogniPep, Cerebropep, Pinealon, PinealPep) – follow dosing in their brand section above

• AM or PM — Pineal Gland: Epitalon, Endoluten (regulate circadian rhythm & lengthen telomeres, anti-aging, over age 18) *see above for Pinealon which is different

-When you first begin (before genetic changes happen), peptides typically have effects only for a few hours, so if you take these at night, they will be more effective. But over time, it could theoretically be taken any time of day, even multiple times.

•••

—> For Vita Stream Liquids / “Linguals”: Use 3-4 drops as equivalent to 1/4 capsule. Refrigerate. They last many months after opening (ignore the 10 days mention on bottle) 🤍

—> For Vita Peptide Blends (Detox, Woman and Man):

Use the same amount as you would individually (1/4 cap of the blend is equal to 1/4 cap of each of the ingredients)

• Blog post for ALL bioregulators: https://diaryofrecovery.com/tinypeps

Other Capsule Peptides (Limitless or Biolab)

Larazotide (LA) – closes tight junctions in gut

  • 1/8 capsule (max 1/4 cap) before meals, sprinkle under tongue or inside another capsule – either way works! Mixed in food, first bite, is ok too.
  • Effects last 2-3 hours (it’s not “healing” – consider KPV / TB4 Frag or bioregulators for healing)
  • Blog: https://diaryofrecovery.com/larazotide-acetate-info/

5 Amino 1 MQ – fat cell metabolism / energy

  • 1/4 cap in morning each day, inside another capsule due to strong taste
  • Storage in the fridge (for this one only) can prolong potency, but constant refrigeration is not needed

Sprays – Nasal or Sublingual (spray under tongue)

For ALL of these we find sublingual use is equally effective to nasal spray & dosing is interchangeable

Must Refrigerate sprays after reconstituting.

For mixing instructions see this page.

Storage before reconstituting is typically room temp.

Selank – anxiety, pain & more

  • 1 spray per day when anxiety is highest, can go up to 3x / day but that is more for acute issues.
  • Lasts ~ 4-6 hours, lasts longer (days or more for anxiety) as use continues
  • Also very useful for pain (head or body aches) or viral illness – give it a try!
  • Effects can be subtle at first – eg. no overreactions to life’s problems.
  • Blog: https://diaryofrecovery.com/selank

Oxytocin – social anxiety

NAD+ – mitochondia (mental and physical energy support), inflammation & more

  • Order Nasal Spray – we find it’s best to use sublingually
  • Dosing varies by deficiency – 1 or 1/2 spray in under tongue, AM or early afternoon, not on empty stomach.
  • Use daily or every other day – based on needs (As your cells recharge, a very, very slight amount of wooziness can be normal first 15 min) 
  • Should notice: increased energy (mental & physical), reduced brain fog, calmer mast cells, & many other benefits!
  • See the blog for ordering details – this one comes premixed, keep it cold.

DSIP – Deep, Restorative Sleep

  • 1/2 to 2 sprays: 1 hour before bed, but requires experimenting. 3 sprays is been used by some and is the “standard” 150 mcg dose

  • Some use it right before bed
  • Some say – slight arousal can occur during first hour after dosing
  • Works equally well sublingually
  • Effects can build, if you begin to feel tired during the day after extended use, consider skipping 1-2 nights
  • Pulse dosing is not required
  • Blog: https://diaryofrecovery.com/dsip

ARA 290 – nerve pain / regeneration

To use 1/2 spray sublingually for any sprays there are two methods we use:

1. Transfer the liquid to an eye dropper bottle and use 1 drop.

It’s estimated that 2-2.5 drops equal one nasal spray but product differences of course make this very inexact!

DSIP is more sensitive to air exposure so opening and closing the bottle may not be ideal. Selank is less sensitive, Oxytocin is mid range.

•••

2. Spray into a small cup and mix with a very small amount of water.

Pour half of that amount into mouth, under tongue, hold in mouth for a short time if possible.

(Also NAD+ but it’s well documented that works sublingually & I wanted to narrow this poll)
We and others have had amazing success with this protocol – sometimes recovery in under a day when started immediately.

It’s applicable for any illness, including severe, alongside needed meds. For example: Chicken Pox / Shingles, combine the above with Valtrex

Links for the above: Thymogen • Selank • Tb4Frag • NAD+ • DSIP

• Adding organ bioregulators (such as Lungs, Kidney, Adrenal etc…) is also a great idea!

• Of course don’t forget vitamins, Red/IR light therapy and all other typical remedies you like!

Purchasing & More

– All links to buy are here: https://diaryofrecovery.com/buy 

– Blog posts with further info on each peptide:

Storage

I keep them in original bottles or if they are in blister packs, I take them out and put them into a push button pillbox.
To dose: I open a capsule, use part of it and put it back in with the others.

Our video about common dosing mistakes and tips is here:

Our page with ALL peptide content is here: