On the outside I looked ok, presentable even.
But my inner health was crumbling and nothing I tried was working.
It wasn’t until I found the world of small molecules and peptides that everything began to improve.
And credit goes to the tiniest of peptides, bioregulators, for taking my health from better to better than ever!
So ~
Even if you’re not 20 anymore
Even if you’re about to give up
Even if your insides feel unpretty
Bioregulator peptides may be the lifeline you’ve been waiting for too!
Skip to list of All 26 bioregulators
This guide will show you:
• How Bioregulator (ultra short-chain) Peptides are are transforming medicine as we know it.
• How to create a DIY Custom Bioregulator Peptide Protocol and heal more than you ever thought possible!
1. Watch the Video walk through
(7 minutes – essential part of this post!)
Tip: The video will continue to play while you scroll this page
Our video explains how to create a DIY protocol with the specific bioregulators you need most!
Video Content: Intro to Bioregulator Peptides // 01:00 List of all 26 available // 01:32 Step 1 // 02:16 Step 2 // 03:02 Unique features of Bioregulators // 04:23 Flashback & Flashforward content // 05:03 A favorite Bioregulator & more // 06:36 Goodbye from us at Belmont Harbor
2. Use this Guide
Contents: (links to corresponding sections)
- The Basics – Bioregs 101
- What & Who they’re best for
- FAQ / Details
- Product lines & discounts
- Plan Drafting (using 2 Steps from video)
- All 26 bioregulators with purchasing info
- Additional content mentioned in our video (links to pages on our site):
- Organ Health Map – Understanding roles and warning signs of each
- 12 Health condition examples – to help conceptualize your plan
- Community challenge (optional!)
- Dr. Holthorf Summary – Bioregulator studies, slides, safety, options for: organ support, anti-aging and aesthetics
For more why they’re safer than longer chain peptides, which you may be more familiar with, see our post here.
Bioregulator Peptides 101
These small peptides naturally support our body’s healing at the cellular level.
They are short chains of 2 to 4 amino acids that are joined by peptide bonds.
•••
They signal our cells to work better, heal faster, or regenerate cells.
Because they are so tiny, they can enter cells easily, reach their target quickly and work immediately.
See our Peptides 101 page for much more about how peptides do their work.
Quick Look 🔍
Here’s what’s coming up in this post ~
Unique Benefits
Bioregulators stimulate the expression of youthful genes and suppress the expression of age and illness-associated genes in ways other options cannot.
Gene Modulation
Their small size allows them to bind to DNA and switch on / off certain genes.
They tell our cells how to produce proteins and carry out functions.
Every bodily system, including digestion, healing, immunity and even thinking all depend on proteins.
Tissue Specificity
Typical supplements are designed to boost overall health but don’t always solve a specific problem.
Bioregulators are targeted. Each one knows exactly where to go.
Peptides à la carte: The bioregulator for the heart goes only to the heart.
Also they only change tissues that need repair.
Healthy / optimal tissues are not affected.
Optimizing Balance
Our body performs best in homeostasis.
Often this balance is disturbed by aging, disease, stress and more. Bioregulators restore our balance so we can heal.
What are they best for?
Most beneficial for people who:
- Want to treat the root cause
- Don’t want to “get it wrong”*
- Want natural options to medicines or are very sensitive
- Are concerned if something can be combined with a medicine (they all can be)
- Want options more effective than herbs without a risk of reactions or unintended (tangential) effects
Because of their limited action, they can be taken with confidence that you’re not “doing it wrong” or will react negatively.
They simply allow our body to reach its optimal state of function.
Real Life Example:
With Bioregulators I treated all of my perimenopause symptoms. I am not using HRT, but even if you are, there’s still room for bioregulators to make further improvements.
You see, adding hormones isn’t addressing a root cause which is organ decline.
Underperforming organs and glands cause more than just lack of hormones.
If we can improve the performance of organs, we can improve our health in ways we never before could!
Skip to list of All 26 bioregulators
FAQ / Details
The concept behind bioregulator peptides is that they align our genes to the best possible “settings.”
After taking them for a while we can try stopping and see how we do on our own!
Over time though, our bodies tend to revert back to how they were before taking the peptides.
That is when a repeat course is needed!
As we use them longer the lasting results (after pausing) remain longer too.
Dosing
• Standard dosing
A 10-30 day course of 1-2 capsules per day, followed by additional 10 day courses as needed.
However, experimentation is encouraged and I have found alternate dosing works better.
• Improved Dosing (we think!)
I base dosing on 3 principles:
- In the beginning, before genetic changes take hold, you’re relying on the direct signaling duration. It is very short (at most 3 hours)
- They are effective even in very small doses.
- Sublingual use allows better absorption
See our page on Dosing tips for more on this topic.
We’ve had incredible results with dosing as follows:
•• Approx 1/4 capsule of powder under tongue / in mouth, several times per day ••
When you are first starting out, I would not take doses at night until you know the effects*
Exceptions:
- Some have a strong taste, I put the powder into another capsule.
- Time of day specific hormonal glands or stimulating:
- AM Only – adrenal, brain / CNS, hypothalamus, pituitary, thyroid
- *PM – pineal (ok to use daytime when in blends)
After using peptides for a while, the genetic changes will take hold and stick.
It’s then that you can space out dosing further.
I take breaks only after I feel I have achieved the benefits I want to see, not on a set schedule.
The first step is to taper the dose(es) and then pause.
If benefits begin to slip, I restart low dosing and see them again within a day or two (quicker than first time using because the genetic effects are remembered)
•••
When you initially begin a bioregulator, some of them can show effects within a few days, but sometimes it can take about a week.
•••
Bioregulator Peptides can be taken with or without food. I have seen both ways being reported as the best!
Natural or synthetic?
Natural contain additional molecules that aren’t the exact peptide chain, but also beneficial to our bodies. Synthetic are only the exact isolated peptide chains.
They are each effective, but some believe natural are slightly more effective and make longer lasting changes.
A benefit of synthetics is the complete lack of taste (easier to dose the powder into the mouth)
Some of them don’t come in a synthetic option.
If you need to avoid porcine, synthetic is the option you will want.
Typically we use natural except where indicated but you can use synthetic and have great results too!
Lingual or capsules?
Sublingual use of peptides allows for faster penetration, greater absorption and accelerated action.
Some bioregulators are sold as either liquid (sublingual) or capsules. We have tried both.
The linguals must be kept refrigerated. The bottle says they are good for 10 days, ignore that, they are fine for 6+ months.
We find that the capsules, with the powder used sublingually or as part of a larger capsule (ok to combine with other supplements) are the best value and convienence.
Combinations?
All Bioregulators can be stacked with each other for synergistic effects.
Exception for time of day specific, noted in dosing above.
Note: Vita Stream offers combination products with 3 peptides in one capsule. Many contain thymus which we don’t take daily.
Some (blends only) contain lactose – if you need to avoid, be sure to check labels.
How quickly can they work?
Often you can see results in two days and certainly less than a week, especially if you are using multiple times per day micro dosing.
For conditions that take longer to heal, you can think about it in terms of how long it would take to heal a wound. Sometimes 1-3 weeks.
Safety?
Peptide bioregulators are generally considered safe, even at high doses with over 40 years of use and reportedly no side effects. See Dr. Holthorf’s info for more.
Does foundation matter?
Yes what we eat, drink, how we sleep and activity levels are still important. ☺️
Bioregulators can work if you change nothing else but will work better the more support you give to your body!
Storage ideas?
I like to either keep them in the original bottles (using empty bottles for ones that come in blister packs)
Or push button pill boxes with 3-4 capsules at a time.
I simply toss the partial capsules right back in with the full ones – remember, dosing is approximate!
Box or bottle?
Sourcing: Which Brand to choose?
Always purchase from reputable suppliers like the ones mentioned here to ensure quality and purity.
Links to buy each we recommend are in the Bioregulator Section.
Lower cost 20 – 30 sizes
If interested be sure to check when ordering for the smallest quantity. Many are available in 20 or 30 ct sizes (larger size is 60ct)
Khavinson (Vita Stream)
Khavinson peptides are “the ones in the white boxes” – they are the OG of the bioregulators and come from Russia.
You can buy them from Vita Stream. Below you will see updated and even more effective options.
Vita Stream also sells linguals and blends.
The links I’m giving are to the individual capsules we use, you can search their site for lingual or combo products.
Vita Peptides (Vita Stream)
Vita Peptides are Vita Stream’s own, USA assembled and tested line. These contain similar bioregulators to the Khavinson offering but are more potent with 50% more active ingredients.
They frequently add new releases and in several cases are peptides you can’t find anywhere else. We appreciate their research and dedication to bringing new products to market!
Examples are: Collagen, Bile & Gastric Mucin. We are always very excited for each new release and they work incredibly well!
Integrative Peptides
Integrative Peptides, in the USA, manufactures bioregulators in custom blends that are Acetylated and Amidated and work better than the Khavinson counterpart. (See our tips page for more info)
Integrative peptides is innovative and heavily invested in research & testing. They continue to develop and add to their line. We love their products and highly anticipate new releases!
Two Steps to Create your Protocol
(Described in: the video)
Two easy steps:
- Detemine which organs / glands are involved in your specific condition or symptoms.
- You can ask AI: (My Digital Mind, Chat GPT, Gork)
- “What are the glands or organ that might be involved in _____[your condition]_____?”
- “My symptoms are ______________ what glands or organs much be the cause?
- For additional ideas and help see our:
- Organ Health Map – Understanding roles and warning signs of each
- 12 Health condition examples – to help conceptualize your plan
- You can ask AI: (My Digital Mind, Chat GPT, Gork)
- Review the list of available Bioregulators (below) and click on the applicable organs.
This page will be updated as additional bioregulators are released!
New information (Sept 2025)
For an AI tool that incorporates ALL of my blog pages, videos, and so much more, you can now instead use my Digital Mind!
Learn more about it here:
26 Available Bioregulators
(Buttons take you to section below)
New kid in town! Plavelle – Placenta Bioregulator – body wide wellness for all. Read our new post on Plavelle.
Adrenals
Top Choice: Adrenact – Vita Peptides
BIOREG10 for 10% off
• Benefits: Supports adrenal function, regulates stress hormones (cortisol, adrenaline, noradrenaline), improves stress resilience, reduces emotional lability, aids metabolism.
Very effective to prevent meltdowns for kids.. or anyone!
• Use: Helps with stress-related conditions, high blood pressure, headaches, and weight gain due to adrenal dysfunction.
• Mechanism: Enhances adrenal gland performance by modulating gene expression for hormone production.
Users Report:
Improved ability to handle stress, and less hormonal imbalances.
Also better sleep, reduced fluid retention, and improved energy for daily activities, “a game-changer for my chronic fatigue; I feel more balanced and less drained after a month” (r/Biohackers)
My Take:
Overwhelm and emotional lability are signs our adrenals need some care. This bioregulator is an excellent choice if you’re exhausted, unmotivated or battling any illness.
It’s especially important during peri- / menopause (when the adrenals take over primary hormone production)
We have found it can replace the need for the glandular adrenal cortex extract.
We use it every morning, 1/4 cap.
Bile
Top choice: Biltorin – Vita Peptides
BIOREG10 for 10% off
Target: Bile and gallbladder
• Benefits: Supports bile production and flow, enhances fat digestion, promotes gallbladder health.
• Use: Helps with gallstones, bile deficiency, fatty liver, digestive issues related to poor fat absorption
• Mechanism: Regulates bile synthesis and secretion by optimizing gallbladder and liver cell gene expression.
Users Report:
It can support bile production and flow, improving digestion and fat metabolism.
People say it reduces gallbladder discomfort and improves liver function but it’s new status means there are few reports!
My Take:
I like it for it’s role in IBS management especially ability to digest fats which has been a trigger for IBS for me.
I’ve also suspected Bile Acid Malabsorptin (BAM) as a cause of IBS-D in the past. I’m still new to using this one but I haven’t had any issues when eating a lot of fatty food (I had to test it out after all!)
Twice a day 1/4 cap
Bladder
Top choice: Chitomur – Khavinson
BIOREG10 for 10% off
Benefits: Normalizes bladder function, improves urine flow, reduces symptoms of overactive bladder syndrome (OBS), benign prostatic hyperplasia (BPH), chronic cystitis
• Use: Supports urinary health, enhances bladder wall flexibility, provides antioxidant effects
• Mechanism: Regulates metabolism in bladder wall cells, reducing oxidative stress.
Users report:
It can improve bladder control, reduce urinary incontinence, interstitial cystitis symptoms (like pain and urgency), and eliminate recurrent UTIs.
Strengthened bladder function and reduced flare-ups, particularly for elderly users with BPH or women post-childbirth, with effects lasting up to 4–6 months after a one-month course.
My Take:
I’ve had a sensitive bladder my whole adult life – interstitial cystitis, oxalate sensitivity, uric acid sensitivity. This bioregulator helps me a very noticeable amount, it’s been a wonderful find for me!
I take 1/4 cap 2-3x per day based on my current need for healing.
Blood Vessels
Top choice: Ventfort – Khavinson
BIOREG10 for 10% off
Synthetic option: Vesugen (buy here)
• Target: Vascular system
• Benefits: Strengthens vascular walls, improves venous tone, enhances blood flow, and supports cholesterol and lipoprotein management.
• Use: Helps with hypertension, varicose veins, and microcirculation issues; promotes healing of traumatized skin.
• Mechanism: Normalizes vascular wall metabolism and structure, optimizing blood pressure and nutrient delivery.
Users Report:
Reduced cholesterol issues. “Ventfort improved my circulation; skin looks better” (r/Peptides, u/HealthNut42); “My legs feel lighter after Ventfort”
Enhanced energy, better wound healing, and support for cardiovascular conditions like hypertension when combined with heart bioregulators.
My Take:
These pair well with and enhance the function of all other peptides and bioregulators.
Because they can help more blood reach the brain, I also consider them critical in the stack that ended my lightheadedness and dizziness – more about this is below.
They can help increase blood flow to other organs as well, of course!
We use: A sprinkle given alongside others (in the same capsule)
Bone Marrow
Top choice: BonoCore – Vita Peptides
BIOREG10 for 10% off
Benefits: Enhances red blood cell production, supports hematopoietic system, and aids recovery from anemia or polycythemia.
• Use: Useful post-illness or treatment (e.g., chemotherapy) to rebuild bone marrow function.
• Mechanism: Balances bone marrow activity by regulating gene expression for hematopoiesis.
Users Report:
bone marrow regeneration, boosting red blood cell production and immune response for anemia or polycythemia. Quotes: “Bonomarlot upped my energy post-illness” (r/Biohackers); “Immune system feels stronger with Bonomarlot”
My Take:
Very noticeably helps with my anemia! 1/4 cap, 1-2x per day
Brain / CNS
Top choice: CogniPep – Integrative Peptides
10% discount at IP: SAVE10 (applies to any product)
CerebroPep – Integrative Peptides
Pinealon (synthetic) – Khavinson
BIOREG10 for 10% off
Pinealon Lingual Version (here)
Pinealeon Blend Spray with Epitalon (here)
Target: Brain and central nervous system (CNS)
• Benefits: These peptides improve brain cell function, enhance oxygenation, slow nerve tissue degeneration, and support cognitive health.
They also give a mental and physical energy boost and increases stamina for both too!
• Uses: Aid recovery from brain injuries, stroke, chronic fatigue, multiple sclerosis, depression, Parkinson’s, and Alzheimer’s. Or just boost your cognition, recall and memory!
• Mechanism: They Regulate CNS gene expression, modulate inflammation, and promote cell growth.
Users Report:
All of the above, countless reports! These are very well studied:
My Take:
We have used all 3 of these brain bioregulators, each with amazing results!
Pinealon (my review here) was an incredible introduction to bioregulators and seeing the cognitive benefits for myself and my daughter made me think, I will never stop using this!
Then, Cerebropep and CogniPep were released and we saw even greater changes.
These bioregulators are no brainers! You only need to select one.
Read about the differences between CogniPep and Cerebropep here
Our dosing: 1/6 to 1/4 cap in morning, 3-4 days a week – sometimes less
They deliver too much energy if we use continually. So breaks are essential.
Sometimes the days “off” are when you will notice gains from these because brain healing can be hard work 🧠
See our blog post here for dosing for kids (or anyone!)
New! See our cheat sheet and video for a deeper dive into these options:
Cartilage
Top Choice: Cartesyl – Vita Peptides NEW!
BIOREG10 for 10% off
Synthetic Option: Cartalax (buy here)
• Benefits: Promotes joint regeneration, reduces pain, improves mobility, and lowers risk of osteoarthrosis, spinal osteochondrosis, and osteoporosis.
• Use: Supports joint and spine health, especially for arthritis or injury recovery.
• Mechanism: Enhances cartilage cell metabolism and trophism, supporting tissue repair.
Users Report:
“Sigumir eased my knee pain noticeably” (r/Biohackers) “Joints feel more flexible with Sigumir”
My Take:
I’ve only used Cartalax but I believe Sigumir is more tested and if you have an issue with cartilage you could use either one.
For my money, Collacell, below is better for joints.
Collagen
Only & Top Choice: Collacell – Vita Peptides
BIOREG10 for 10% off
Target: Skin, joints, and connective tissues
• Benefits: Promotes collagen production, improves skin elasticity, reduces wrinkles, and enhances joint mobility and strength.
• Use: Helps with aging skin, joint discomfort, and connective tissue degeneration; supports hair and nail health.
• Mechanism: Stimulates collagen synthesis by regulating gene expression in skin and connective tissue cells.
My take: (A Favorite!)
The texture of my skin was smoother, softer and feeling more elastic after using this bioregulator for only 2 days!
After two weeks, I noticed certain areas slightly but noticeable lifted – cheeks, upper lip, chest. My skin tone seems to be evening too (less freckles)!
After 4 weeks it’s gravity reversing effect above eyes, at cheekbones and tightening of my skin everywhere is undeniable.
It’s the most effective beauty product I’ve ever used!
Not to be confused with taking collagen peptide powder (broken down collagen), collagen bioregulators stimulate the body’s production of collagen and elastin.
Collagen bioregulators have performed very well in studies and are shown to:
- Support and maintain skin, joint, muscle and overall connective tissue health
- Can help improve skin elasticity and reduce the appearance of wrinkles
- Can also help regulate hormonal balance and improve cellular metabolism
My Dose: The powder from 1 full capsule divided several times through the day, under the tongue
It has no taste and I use it morning through night no side effects.
Gastric Mucin
Only & Top choice: Gastrogen – Vita Peptides
BIOREG10 for 10% off
Target: Stomach & Intestine lining and gastric mucin
• Benefits: Supports the protective mucus layer in the stomach and intestines, helps defend against acid & irritation.
Promotes healing of the gastric lining and microbial balance. Helps with Acid Reflux, GERD
Prevents ulcers and inflammation.
• Use: Ideal for those with sensitivity to stomach acid, gastritis-like symptoms, or needing protection of the stomach lining.
Helps also with peptic ulcers and digestive discomfort due to poor mucosal protection.
• Mechanism: Regulates gastric mucin production and cell metabolism via gene expression.
FAQ: how does it help with Acid Reflux Specifically?
- Protective barrier: Mucin forms a viscous layer over the stomach and esophageal lining, shielding it from acidic gastric contents and pepsin.
- Reduces irritation: Enhances mucosal defense, limiting damage from reflux.
- Promotes healing: Supports repair of damaged esophageal tissue by maintaining a stable pH gradient.
- Anti-inflammatory: May reduce inflammation caused by refluxed contents, aiding in symptom relief.
- Research support: Studies show mucin protects gastric epithelium from acid and pepsin damage.
Users Report:
Reduced acid reflux, heartburn, intestinal upset and ulcer risk while supporting digestion.
“Gastric peptides eased my reflux quickly” “Stomach feels calmer with mucin peptides”
My Take: (my Daughter’s Favorite!)
My daughter who has acid reflux issues (at times very severe), has not had them while using it!
I feel my intestinal sensitivity has calmed even more than before.
1/4 cap, 2-3 x per day
Read our NEW Gastrogen Blog Post!
Heart
Top Choice: Kardium – Vita Peptides
BIOREG10 for 10% off
• Target: Heart muscle and cardiovascular system
• Benefits: Strengthens heart muscle, regulates cardiovascular function, and supports heart health.
• Use: Helps with coronary artery disease, hypertension, myocarditis, atrial fibrillation, and heart failure.
• Mechanism: Normalizes heart muscle metabolism and gene expression for cardiovascular health.
Users Report:
Manages conditions like hypertension and “Chelohart boosted my stamina” (r/Biohackers) “Heart feels stronger with Chelohart”
My Take:
I have noticed both of the above too!
1/4 cap per day – more if you have heart issues Consider combining with Tb4 Frag
Hypothalamus
Only & Top choice: Hypotalen – Vita Peptides
BIOREG10 for 10% off
• Benefits: Supports hypothalamic function, regulates hormone production, and promotes homeostasis, including sleep, appetite, and stress response.
• Use: Helps with hormonal imbalances, sleep disorders, and stress-related conditions.
• Mechanism: Enhances hypothalamic cell metabolism and gene expression to optimize endocrine regulation.
Users Report:
Balanced hormones improved mood, energy, and stress response via neuroendocrine support.“Hypothalamus peptides lifted my mood” (r/Peptides) “Energy’s up since starting these”
My Take: Critical! See Pituitary Section
Kidneys
Top choice: Rhenolux – Vita Peptides
BIOREG10 for 10% off
• Benefits: Normalizes kidney function, reduces uric acid and urea levels, and supports renal health.
• Use: Helps with gout nephropathy, urolithiasis, renal failure, and chronic pyelonephritis.
Excellent for assisting with
die off removal (especially combined with liver)
May also be used in combination with the Bladder and Blood Vessel Bioregulators.
• Mechanism: Regulates kidney cell metabolism and gene expression to enhance filtration and detoxification.
Users report:
“Helped my kidney function” (r/Biohackers)?; “Urination’s easier and gout arthritis in joints much less intense”
My take:
It helps immensely with reducing my uric acid levels from eating too much animal protein – causing feelings similar to interstitial cystis and joint pain – both are noticeably reduced.
For how it aids detox see liver section below.
Both the kidneys and liver help remove toxins from bacterial die-off (a Herxheimer reaction).
The liver processes and neutralizes them first, making them easier to eliminate, while the kidneys filter the blood and flush out the water-soluble waste through urine.
Liver
Top choice: Liverra – Vita Peptides
BIOREG10 for 10% off
Synthetic Option: Ovagen (buy here)
Benefits: Supports liver function, enhances detoxification, and promotes liver cell regeneration.
• Use: Useful for hepatitis, fatty liver, and liver damage from toxins or alcohol.
It also helps with fatigue and digestive issues. It may benefit those with atherosclerosis, diabetes, and obesity.
• Mechanism: Regulates liver cell metabolism and gene expression for repair and detoxification.
Users report:
Aids recovery from liver damage or fatty liver disease. “Svetinorm cut my fatigue a lot” (r/Peptides) “Digestion’s better with Svetinorm”
My Take:
Struggling to detox is not unusual for my daughter and at times her skin will be very slightly yellow-ish.
Ovagen, combined with the kidney bioregulator visibly helped her detox and she was back to normal color in about 2 days!
Our Dose: 1/4 cap each per day
Combining stomach, pancreas and liver can provide comprehensive GI support.
Lungs
Top choice: LunGuard – Vita Peptides
BIOREG10 for 10% off
Synthetic Option: Chonluten (buy here)
Target: Lungs and bronchial mucosa
• Benefits: Supports lung function, enhances oxygen exchange, reduces inflammation, and promotes respiratory health.
• Use: Helps with chronic bronchitis, bronchial asthma, smoker’s cough, and chronic obstructive pulmonary disease; aids recovery post-respiratory illness.
• Mechanism: Regulates bronchial mucosa cell metabolism and gene expression to optimize respiratory function and tissue repair.
• My Take: (Another favorite!)
I’ve used Taxorest and Chonluten and now LunGuard for my allergic asthma.
While KPV was keeping it under control, I wanted to take a break from KPV.
Not only are my lungs asthma free, they have a capacity I did not know was possible – I understand now how people can sing!
(LunGuard does also have a taste but I still use it under the tongue)
My Dose: I took about 1/5 of a capsule under the tongue several times a day for approximately 6 months.
Recently, I added it to my daughter’s stack because she was coughing after being sick. It helped quicker than anything else I’ve ever tried.
For Asthma:
The combination of both KPV and a Lung bioregulator is be best for someone just starting to treat asthma.
After a few months I was able to switch to just the bioregulator and then take breaks from that too.
Muscles
Top choice: GoTratix – Khavinson
BIOREG10 for 10% off
• Benefits: Enhances muscle strength, reduces fatigue, improves physical performance, and supports muscle recovery; helps combat age-related muscle loss (sarcopenia).
• Use: Supports athletes, individuals with intense physical activity, and those with muscle weakness or mobility issues.
• Mechanism: Regulates myocyte metabolism and gene expression to optimize muscle tissue function, enhance endurance, and promote repair.
Users Report:
“Gotratix speeds my muscle recovery” (r/Peptides) “Workouts feel easier with Gotratix”
My Take:
The studies are impressive! For me, it helped me recover from debilitating siatica from a muscle strain. (Piriformis Syndrome) The more frequently I dosed (up to 5x a day) the better I felt.
See https://diaryofrecovery.com/biovideo for info on long jump, grip strength etc..
Typical starting dose: 1/4 cap, 2-3x per day
Ovaries
Top choice: Ovalis – Vita Peptides
BIOREG10 for 10% off
Until 8/18/25: 15% off with VITAPEP15
• Benefits: Supports ovarian function, promotes hormonal balance, and enhances reproductive health; may ease menstrual and menopausal symptoms.
• Use: Helps with hormonal imbalances, menopausal symptoms, and fertility issues; supports skin health and mood stability.
• Mechanism: Enhances ovarian cell metabolism and gene expression to optimize hormone production and maintain reproductive system health.
Users Report:
“balanced my cycles” (r/Biohackers, u/FertilityHope); “Menopause symptoms eased”
My Take:
I love it for menopause! Helps with feeling vibrant, dryness, hot flashes and more subtly also with: skin elasticity, fatigue, brain fog.
See my post about Hormone Support over age 40 for much more on this one!
My dose: 1/3 -ish cap in morning, you could take more if you like!
(Just a Note – For PMS /PMDD especially pain, my daughter has great success with Selank.)
Pancreas
Top Choice: Suprefort (included in Gastro)
BIOREG10 for 10% off
Benefits: Improves pancreatic function, supports insulin production, and aids digestive enzyme regulation.
• Use: Effective for chronic pancreatitis/type II diabetes, lowering blood sugar in diabetes and supporting pancreatic tissue recovery.
• Study of 34 patients 15 days: Enzymes increased (trypsin 2.9 mmol/L); glucose 7.0 mmol/L post-load.
• Mechanism: Enhances pancreatic cell metabolism and gene expression for hormone and enzyme production.
Users Report:
“Suprefort stabilized my blood sugar” (r/Peptides) “Digestion’s smoother with Suprefort”
My Take:
Again, I sgeee with the above, my digestion was notably improve when I began.
We also take this one because it combines well with Stomach and Liver and we take both of those!
1/4 cap each, 2x per day – can consider GASTRO Blend at Vita Stream
Parathyroid
Top choice: Bonothyrk – Khavinson
BIOREG10 for 10% off
• Benefits: Regulates calcium and phosphorus metabolism, supports bone health, aids parathyroid function & bone tissue restoration.
• Use: Helps with osteoporosis, hypoparathyroidism, and calcium imbalances.
• Mechanism: Modulates parathyroid hormone production via gene expression.
• Effective for osteoporosis prevention, esp. women >50.
• Study: 33 women (47-56) with low bone density, 30 days: Bone demineralization slowed; BMD decrease >20% reduced from 9.5% to 5.3
Users Report:
“Bonothyrk reduced my cramps” (r/Biohackers) “Bones feel stronger with Bonothyrk”
I love this for the bone health women over a certain age 🙂
1/4 cap, 2x a day for me!
Pineal (Endocrine)
Top choices:
(Blends) PinealPep OR Epitalon – Pinealon Spray (my review of these is here)
Integrative Peptides
- Save10 for 10% off
(Pineal only – natural) Endoluten – Vita Stream
- BIOREG10 for 10% off
(Pineal only – synthetic) Epitalon Capsules – Limitless
- Use Code: QUALITY for 20% off
• Target: Pineal gland
• Benefits: Regulates melatonin production, improves sleep quality, enhances circadian rhythms, and supports anti-aging via telomere lengthening.
• Use: Aids sleep disorders, jet lag, and age-related decline; may have anti-cancer properties.
• Mechanism: Stimulates pineal gene expression and telomerase activity.
My Take:
Epitalon-Pinealon Spray: 1-2 drops in the morning 5 days on / 2 days off then taper See this review for much more info: https://diaryofrecovery.com/brain
PinealPep: 1/8 – 1/4 cap day or evening, experiments needed because the blend could be stimulating for some
Endoluten / Epitalon: 1/4 – 1/2 cap, 1-2 hours before bed – these are single focus pineal products so can be taken at night.
Here’s an example from our review post of how many of the bioregulator peptides have cascading effects.
Pituitary
Top & Only Choice: Endocron – Vita Peptides
Code BIOREG10 for 10% off
Benefits: Supports pituitary function, regulates hormone secretion (e.g., growth hormone, ACTH), and promotes endocrine balance.
• Use: Helps with hormonal disorders, stress response, growth issues, and pituitary-related fatigue or dysfunction.
• Mechanism: Enhances pituitary cell metabolism and gene expression to optimize
• My Take:
One of my most favorite peptides!
Despite the name, it is not related to endoluten or the pineal gland.
The pituitary is a small but powerful gland at the base of the brain, regulating many critical body functions, including metabolism, growth, and the reproductive system.
It’s an important bioregulator for anyone concerned with hormone production and extremely valuable for peri & menopause symptoms.
•••
My personal Example Combination Protocol for Allergies
I started taking it when I wanted to try a break from KPV and was concerned about how my mast cells might react.
Choosing endocron as a possible stand-in was based on a theory that the HPA axis (hypothalamus-pituitary-adrenal) can regulate allergic inflammation.
I take:
Adrenact (adrenals) above – 1/4 cap in morning only
Endocron (pituitary) – 1/3 cap total, morning
Hypothalamus bioregulator (above) – 1/3 cap per day morning only
This HPA bioregulator combination definitely seems to work to keep my allergies extremely low ~ not as effectively as KPV (which for me results in total elimination) but surprisingly well!
It could have a positive imact for anyone with suspected HPA dysfunction.
“Some of the general symptoms of HPA dysfunction include:
- Feeling irritable
- Frequent illnesses
- Difficulty coping with stress
- Feeling unexplainable tiredness
- Feeling overwhelmed
- Experiencing an exaggerated response to stress” (Source)
In other words. We could all have this!
I have seen improvement in every item on the list while taking these peptides.
My daughter is also showing a much improved response to stress.
To recap – Endocron is designed support:
• the endorcine system • healthy metabolism • sleep patterns • mood • cognitive functions • a healthy response to stress •
Prostate
Top choice: Prostalon – Vita Peptides
BIOREG10 for 10% off
• Target: Prostate gland
• Benefits: Supports prostate health, reduces inflammation, and improves urinary function.
• Use: Helps with benign prostatic hyperplasia (BPH), prostatitis, and sexual dysfunction.
• Study: 48 men (38-65) prostatitis/BPH: Pain improved 64%; sexual function improved 44%; urination rate 23.5 ml/s.
• Mechanism: Regulates prostate cell metabolism and gene expression to reduce hyperplasia.
Users Report:
“Libidon eased prostate and night urination” (r/Peptides)
Retina / vision
Top choice: Visoluten – Khavinson
BIOREG10 for 10% off
• Target: Retina and eyes
• Benefits: Supports retinal health, improves visual acuity, and slows age-related vision decline.
• Use: Helps with macular degeneration, diabetic retinopathy, and eye strain.
• Mechanism: Enhances retinal cell metabolism and gene expression for visual function.
Users Report:
In groups, people have reported it can improve vision clarity, color contrast, and night vision, with some experiencing faster recovery post-LASIK and reduced floaters or scarring effects.
A few report significant vision improvements, such as from 20/20 to 20/10, and even restored sight in severe cases after consistent use.
Worth a try for anyone with visual function issues.
Stomach
Top Choice: Stomek – Vita Peptides
BIOREG10 for 10% off
Benefits: Supports gastric mucosa, improves digestion, and aids ulcer healing.
• Use: Helps with gastritis, ulcers, and digestive discomfort.
• Mechanism: Regulates stomach cell metabolism and gene expression for mucosal repair.
User Reports:
“Stopped my heartburn” (r/Biohackers) “No more bloating with Stamakort / Stomek”
My Take:
I like it! I can’t say that I “noticed” anything other than my stomach feeling great / settled.
Our Dose: 1/4 cap once or twice a day
* I originally took a approx 1/6 cap before every meal (combined with Pancreas).
Testes
Top choice: Testovive – Vita Peptides
BIOREG10 for 10% off
• Benefits: Supports testosterone production.
Poor testicular performance can manifest in various ways, including sexual dysfunction, mood changes, decreased energy, and physical changes like muscle loss.
• Use: Helps with low testosterone, aging, irritability, infertility, and ED.
• Mechanism: Regulates testicular cell metabolism and gene expression for hormone production.
My Take:
See my post about Hormone Support over age 40 for much more on this one!
Users Report:
Better than TRT because that can shrink testes due to the lowering the body’s need to produce testosterone – more here.
Improved fertility, and muscle mass in men.“Testoluten upped my energy, libido” (r/Peptides) “Feel stronger with Testoluten”
Thymus
Top choice: Thymogen Alpha 1 – Integrative Peptides
10% Discount: SAVE10
It contains two Thymus bioregulators: Thymogen and Vilon.
Target: Thymus gland and immune system
• Benefits: Boosts immune response, enhances T-cell production, reduces inflammation, and supports tissue repair.
• Use: Helps with infections, autoimmune conditions, and immune decline in aging.
• Mechanism: Stimulates thymus gene expression for immune cell production.
My take:
Thymogen has been extremely helpful for us whenever we get sick, lately almost miraculously so!
With it, we’ve had no post viral flares!
It’s an important part of our PANS protocol.
Our Dose (when sick): 1/4 cap, 2-3x a day
If you are not Th1 dominant it can be used more often!
Please see my more detailed review here:
https://diaryofrecovery.com/review/#thymogen
Thyroid
Top choice: ThyroPep – Integrative Peptides
10% Discount: SAVE10
• Benefits: Supports thyroid function, regulates hormone production, and improves metabolism.
• Use: Helps with hypothyroidism, hyperthyroidism, and thyroid-related fatigue.
• Mechanism: Enhances thyroid cell metabolism and gene expression for hormone balance.
My Take:
It gave me increased energy, better sleep, temperature regulation, brought stability to my body (not so sensitive to everything) and turned around the last of my remaining health issues.
Optimizing your thyroid can also decrease brain fog.
Reasons ThyroPep works dramatically better than the Thyroid Bioregulators you will see below:
- It’s Acetylated and Amidated – more bioavailable, lasts longer, closer matches our own peptides.
- It contains bioregulator peptides and glandulars – with T4 and T3 removed.
- It contains additional (3 total) bioregulators.
- See my post below and this video I made for my comparison of each
It can be taken by people with hypo or hyper thyroid conditions and / or autoimmune thyroid issues such as Hashimoto’s) and bring all of us back to balance!
I use: 1 cap every morning.
Please see more of my review here: https://diaryofrecovery.com/review/#thyropep
This post is long! If you made it to the end, thank you for being here. 🤍
I hope you find the tools you need to create your best bioregulator plan to restore your health!
ALL of our Peptide Content can be found at this page:
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