Over the years we’ve tried 99% of the non-pharmaceutical options for anti-anxiety and some prescription meds too.
Selank is non-prescription and works extremely well!
Better than any other natural option we’ve tried.
And many people claim it works better than meds — with NONE of the side effects.
No grogginess, fogginess or slow thinking.
No addiction or withdrawal problems, just clean, pure calm!
Too good to be true? Almost!
The only caveat is, when you’re first starting out it can need more frequent dosing for the effects to last all day.
But recent updates have resulted in a version that lasts longer than original Selank.
We’ll tell you all about the version you want, how to dose it and more in our video:
Tip: The video will continue to play while you scroll this page
Video Notes
These notes are provided so you don’t need to take them during the video. More is covered in the video than listed here!
(Click links to skip to each topic below)
- Who it helps
- Our experience
- How it works (science lite!)
- Where to buy (and which version – this is key)
- Dosing options (including sublingual & drops)
NEW – Consider our AI Tool!
Who can benefit from Selank?
People experiencing (daytime or nighttime):
- Anxiety, stress, nervousness
- Excessive worry, ruminations
- Overactive mind, ADHD, ADD
- PMS, PMDD
- Depression, Mood regulation challenges
- Fight or flight, dysregulated nervous system
- Panic attacks, even panic induced rage / aggression
- Pain (see below)
Specific Examples:
Sleeplessness due to any issues above (also – because it’s non sedating, no worry about taking it too close to when you need to wake up)
Brain Fog or headaches related to above
Waking up with a racing heartbeat in the morning from a spike in cortisol
Pain Relief: My daughter had severe menstrual cramps, didn’t want to eat. Two minutes after using Selank was up doing a workout program and requesting food!
We’ve also observed it working exceptionally well for pain related to being sick – it completely takes away body aches, pains and fevers. It’s also reported to help as an antiviral, by group members and noticed by us recently too!
•••
• Note: Effects can also be subtle – reports of “doused with common sense” and no overreactions to life’s problems. (analogy, no crying over spilled milk, just calmly clean it up)
What’s Selank, and Why Should You Care?
Selank is a synthetic peptide based on a natural peptide called tuftsin, which our body already makes tied to immune function.
Selank it’s 7 amino acids long with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. (There won’t be a test on this!)
The longer the peptide, the more succeptible it is to breaking down.
7 amino acids is a moderate length and below we talk more about recent updates to make it stronger.
•••
This peptide not only reduces anxiety and boosts mood, it can also sharpen memory, reduce inflammation and improve our immune systems.
How does a tiny spray work so well?
Selank delivers calm without the crash by:
- Influencing GABA receptors — an inhibitory neurotransmitter system in the brain
- Modulating the balance of dopamine and serotonin — promoting a sense of steady calm and well-being
- Altering the expression of genes involved in stress response pathways — improving ability to manage stress
- Guarding enkephalins — stops enzymes from breaking down our natural pain killing and mood-lifting peptides. (why it helps with headaches)
- Positively influencing brain-derived neurotrophic factor (BDNF) — a protein essential for healthy cognition and mood
- Modulating cytokines — by reducing inflammation a cascade of improvements can result
Also intriguing is its immunomodulatory benefits and potential to support overall wellness.
This article is an excellent summary of everything you want to know about Selank, with research even mentioning GI health, fewer ulcers and reduction of cancer tumor growth.
Our Experience
Please watch the video for an explanation of how well it benefits us!
Briefly:
• For my daughter, it significantly decreases anxiety, panic, fight-or-flight, OCD & fixation on ideas.
• I’m often surprised at how well and how quickly (5-10 minutes) it works!
• If I am awake in the night and can’t sleep, it stops my restless mind and I can easily fall back asleep. (It does not itself cause drowsiness)
• Updated Info: After using Selank for a while (over a month for me, over 6 months for my daughter), I have noticed that the effects don’t fade nearly as quickly — they can last more than a day and for me almost up to a week!
The epigentic changes are responsible!
Our Dosing
Our spray is 300 mcg per spray
We typically use 1 spray as needed – only one side of the nose
- Anytime, day or night (or both!)
- It works rapidly (under 10 minutes)
- Effects usually taper after 4-6 hours
- We have also used: 200 mcg (it works too) and 400mcg for greater chill!
•••
Some people use it 2-3x per day
Some find it “resets” them and they can take extended breaks from use
Note: there have been a few people in our group who reported that it didn’t work right away, but when they kept taking it for about a week, it began really working well! So experimentation seems key 🤍
This is not medical advice and people do give it to their children, often using a lower dose.
Alternate Dosing
It can be tried sublingually – in the video I explain how that went for my daughter years ago.
It can also be used as nasal drops, shown in the video too.
Upper limit tested is much higher than what we have used:
Reconstitution & Storage
The peptide spray will need to be mixed when it arrives.
We have a page to help you with that here:
^ There is a video reconstitution demo on that page and some tips!
After you reconstitute it, it should be kept refrigerated.
We keep it for a few months (in the fridge) while we use it.
Are breaks needed?
There are no studies finding that you need to take breaks or that the GABA receptors become sensitized but some people theorize they may.
It can be pulsed and time off can be taken, experimenting is the best way to find out what’s best for you!
•••
We typically prefer lower consistent doses and only very short breaks over starting and stopping for most peptides we use.
My daughter’s been using it almost daily for a few months, most commonly 1 spray per day, sometimes 2.
I use it on and off, typically if I have trouble sleeping — it’s great if you don’t want to take a sleep aid, especially if it’s closer to the time you need to be awake.
We do NOT use this much and daily 🙂
Advantages over traditional treatments:
- Selank is viewed as an excellent alternative to traditional anxiety treatments like benzodiazepines and barbiturates
- It lacks the sedating or cognitive side effects, addiction potential, and withdrawal problems
- Here’s one persons very positive experience:
Also check this out!
Regular Selank vs. N-Acetyl Selank Amidate
An upgraded version!
(A compounding pharmacy does not have this one)
Why is this important?
- Acetylation slows enzymes from breaking it down – lasts longer
- Amidation alters the charge and ‘stickiness,’ helping it reach deeper into the brain – more effective
- It more closely matches the natural peptides our bodies produce
With an acetyl group on one end and an amide on the other, it’s more effective and can last longer at lower doses.
- More bioavailable, better absorbed
- More stable, resists breakdown / lasts longer in your system
- More effective at lower doses
- Better able to cross the blood brain barrier
Where to purchase / coupon codes
Note: If you’ve tried it in the past or are using a version from a compounding lab, it’s unlikely to be acetylated and amidated – which is a game changer for how well it works.
It’s best to buy from a peptide company direct, like Limitless.
Limitless Biotech
The company is well respected, third party tested and offers certificates of analysis.
Link to product: Selank at Limitless website
Coupon code: QUALITY for 20% off
Free shipping in USA for a limited time.
*You DON’T need to purchase any additional items – it comes with the water, syringe and sprayer.
- Available in both 200 mcg or 300 mcg per spray versions
- We have used both
- If you purchase the 20mg (200mcg dose) bottle, you can use 2 sprays to equal 400mcg — or you could mix it with just 3/4 of the water provided for more potency.
- Also ship to many other countries, they are listed at the checkout
Note: If you are overseas, you will not get a syringe – customs won’t allow it.
Biolab, UK Option
No longer shipping to the USA
Also, they don’t have an Amidated version
The product is half the strength of the 300mcg offered at Limitless
**Each spray will be 150 mcg so adjust accordingly.**
Link to product: Selank at Biolab site
Coupon code: RESTORE will get you a discount
It might be your next best discovery too!
Selank has my daughter calmer, more focused, and living her best life!
I feel very happy to have a sleep aid and anxiety booster I can count on day or night!
No sedation, no addiction — just pure chill. 🧘🏼♀️
Thank you for joining us today!
If you have questions, the best way to reach us is with a comment on the YouTube video page
And for more on all of the 41 different peptides we’ve tried, you can see this post!
•••
Update: So many wonderful stories of success are coming in the group, keep them coming, we are so happy to hear them! 🤍
Here are just two examples:
You may also like — Our Resources Page with all of our Peptide related content!
^ At this page you will find collections of studies for peptides too, including Selank.
For more Sleep specific help, consider DSIP Peptide 🌙
blog_subscription_form]
References
Don’t miss This article — an excellent summary of Selank benefits with research even mentioning GI health, fewer ulcers and reduction of cancer tumor growth.
Here’s what’s included:
- Volkova, A., et al. (2021). “Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission.” Frontiers in Pharmacology. —- How Selank affects gene expression related to neurotransmission, supporting its anxiety-reducing and cognitive effects.
- Shevchenko, K. V., et al. (2023). “Comparative Analysis of Selank and N-Acetyl Selank Amidate: Stability and Neuroprotective Effects in Animal Models.” Neuroscience and Medicine. — How N-Acetyl Selank Amidate’s enhanced stability might amplify those benefits, particularly for mood regulation and memory.
- Zozulya, A. A., et al. (2008). “Efficacy and Possible Mechanisms of Action of Selank in Anxiety Disorders.” Zhurnal Nevrologii i Psikhiatrii, 108(4), 38-48.
- Kolomin, T. A., et al. (2013). “A New Generation of Drugs: Synthetic Peptides Based on Natural Regulatory Peptides.” Russian Journal of Bioorganic Chemistry, 39(4), 413-418.
- Zh Nevrol Psikhiatr Im S S Korsakova (2008) shows it’s safe with few to no side-effects.
You can find many more research references in the above article link.
Discover more from Diary of Recovery
Subscribe to get the latest posts sent to your email.
Diary of Recovery 
hi Rebecca thank you for sharing this , I am trying to order selank from limtless but they require a payment via wire transfer is that your expirience_?
thank you
Hi, I have used a credit card with limitless – I’d give them a call they are very responsive!